Results 121 to 130 of about 191,946 (295)
FishesThe obscure puffer (Takifugu obscurus) is a popular cultured species and accounts for around 50% of the total pufferfish production in China. A hybrid puffer was generated by crossing a female obscure puffer with a male tiger puffer (T. rubripes).
Chaoyu Wang +8 more
doaj +1 more source
PLoS ONE, 2019 Genomic regions subjected to selection frequently show signatures such as within-population reduced nucleotide diversity and outlier values of differentiation among differentially selected populations.
Salvatore Mastrangelo +12 more
doaj +1 more source
Identifying signatures of recent selection in Holstein cattle in the tropic
Revista Colombiana de Ciencias Pecuarias, 2018 Background: Holstein cattle have undergone strong selection processes in the world. These selection signatures can be recognized and utilized to identify regions of the genome that are important for milk yield.
Juan C. Rincón +2 more
doaj +1 more source
Measurement Selection for Engine Transients by Parameter Signatures [PDF]
, 2010 A method of measurement selection is introduced that relies on parameter signatures to assess the identifiability of dynamic model parameters by different outputs.
James R. McCusker, Kourosh Danai
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Selection signatures in ancestral populations. [PDF]
, 2014 SNP with significant FLK value at the 5% FDR level, with estimated allele frequencies in all ancestral groups. The number of genes included in each region (1Mb up-or-downstream the position) and the rank of candidate genes within the region is also ...
Rachel Rupp (210779) +6 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Selection signatures in sheep [PDF]
Natural selection pressure favors animals that are better adapted to certain environments. Artificial selection aims to meet the economic needs of animal production. Both affect genetic diversity and can cause genomic modifications in animals.
Rodrigues, Julia Lisboa [UNESP]
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