Results 51 to 60 of about 179,723 (264)

Selection signatures for high‐altitude adaptation in ruminants [PDF]

Animal Genetics, 2020
SummaryHigh‐altitude areas are important socio‐economical habitats with ruminants serving as a major source of food and commodities for humans. Living at high altitude, however, is extremely challenging, predominantly due to the exposure to hypoxic conditions, but also because of cold temperatures and limited feed for livestock.
J. Friedrich, P. Wiener
openaire   +3 more sources

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Selection Signature Analysis of Whole-Genome Sequences to Identify Genome Differences Between Selected and Unselected Holstein Cattle

Animals
A unique line of Holstein cattle has been maintained without selection in Minnesota since 1964. After many generations, unselected cattle produce less milk, but have better reproductive performance and health traits when compared with contemporary cows ...
Jiarui Cai, Liu Yang, Yahui Gao, George E. Liu, Yang Da, Li Ma   +5 more
doaj   +1 more source

Selecting Parameters for the Rainbow Signature Scheme [PDF]

, 2010
Multivariate public key cryptography is one of the main approaches to guarantee the security of communication in a post-quantum world. One of the most promising candidates in this area is the Rainbow signature scheme, which was first proposed by J. Ding and D. Schmidt in 2005.
Albrecht Petzoldt, Stanislav Bulygin, Johannes Buchmann 0001   +2 more
openaire   +1 more source

Selection signatures in Canchim beef cattle [PDF]

Journal of Animal Science and Biotechnology, 2016
Recent technological advances in genomics have allowed the genotyping of cattle through single nucleotide polymorphism (SNP) panels. High-density SNP panels possess greater genome coverage and are useful for the identification of conserved regions of the genome due to selection, known as selection signatures (SS).
Urbinati, Ismael, Stafuzza, Nedenia Bonvino, Oliveira, Marcos Túlio, Chud, Tatiane Cristina Seleguim, Higa, Roberto Hiroshi, Regitano, Luciana Correia de Almeida, de Alencar, Maurício Mello, Buzanskas, Marcos Eli, Munari, Danísio Prado   +8 more
openaire   +3 more sources

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Genomic Uniqueness of Local Sheep Breeds From Morocco

Frontiers in Genetics, 2021
Sheep farming is a major source of meat in Morocco and plays a key role in the country’s agriculture. This study aims at characterizing the whole-genome diversity and demographic history of the main Moroccan sheep breeds, as well as to identify selection
Abdessamad Ouhrouch, Abdessamad Ouhrouch, Simon Boitard, Frédéric Boyer, Bertrand Servin, Anne Da Silva, François Pompanon, Abdelmajid Haddioui, Badr Benjelloun   +8 more
doaj   +1 more source

Screening for epistatic selection signatures: A simulation study [PDF]

Scientific Reports, 2019
AbstractDetecting combinations of alleles that diverged between subpopulations via selection signature statistics can contribute to decipher the phenomenon of epistasis. This research focused on the simulation of genomic data from subpopulations under divergent epistatic selection (ES).
Id-Lahoucine, Samir, Molina Alcalá, Antonio, Cánovas, Ángela, Casellas, J.   +3 more
openaire   +6 more sources

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge, Maite E. Houwing, Rowena L. Grohssteiner, Ferdows Atiq, Sonja A. M. C. Teuben, Mirjam P. Fransen, Marjon H. Cnossen   +6 more
wiley   +1 more source

Selective sweep analysis reveals extensive parallel selection traits between large white and Duroc pigs

Evolutionary Applications, 2020
In the process of pig genetic improvement, different commercial breeds have been bred for the same purpose, improving meat production. Most of the economic traits, such as growth and fertility, have been selected similarly despite the discrepant ...
Saixian Zhang, Kaili Zhang, Xia Peng, Huiwen Zhan, Jiahui Lu, Shengsong Xie, Shuhong Zhao, Xinyun Li, Yunlong Ma   +8 more
doaj   +1 more source