Results 111 to 120 of about 98,515 (154)

Correction: The circROBO1/KLF5/FUS feedback loop regulates the liver metastasis of breast cancer by inhibiting the selective autophagy of afadin. [PDF]

Mol Cancer
Wang Z, Yang L, Wu P, Li X, Tang Y, Ou X, Zhang Y, Xiao X, Wang J, Tang H.   +9 more
europepmc   +1 more source

Decoding the molecular mechanism of selective autophagy of glycogen mediated by autophagy receptor STBD1. [PDF]

Proc Natl Acad Sci U S A
Zhang Y, Sun Y, Shi J, Xu P, Wang Y, Liu J, Gong X, Wang Y, Tang Y, Liu H, Zhou X, Lin Z, Baba O, Morita T, Yu B, Pan L.   +15 more
europepmc   +1 more source

RCHY1 and OPTN are required for melanophagy, selective autophagy of melanosomes. [PDF]

Proc Natl Acad Sci U S A
Lee KW, Ryu KJ, Kim M, Lim S, Kim J, Kim JY, Hwangbo C, Yoo J, Cho YY, Kim KD.   +9 more
europepmc   +1 more source

The connection between autophagy and ferroptosis in AKI: recent advances regarding selective autophagy. [PDF]

Ren Fail
Pan C, Zhao H, Cai X, Wu M, Qin B, Li J.
europepmc   +1 more source

CSNK2/CK2 regulates selective autophagy of the endoplasmic reticulum. [PDF]

Autophagy
Stolz A.
europepmc   +1 more source

Correction: Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy.

Elife
Grumati P, Morozzi G, Hölper S, Mari M, Harwardt MIE, Yan R, Müller S, Reggiori F, Heilemann M, Dikic I.   +9 more
europepmc   +1 more source

A role for selective autophagy of the ER in gametogenic rejuvenation revealed by microfluidics-based lifespan profiling

Spiri S, Sing TL, Phung N, Goodman JS, Ünal E, Brar GA.   +5 more
europepmc   +1 more source

Mechanisms of Selective Autophagy

Annual Review of Cell and Developmental Biology, 2021
Selective autophagy is the lysosomal degradation of specific intracellular components sequestered into autophagosomes, late endosomes, or lysosomes through the activity of selective autophagy receptors (SARs). SARs interact with autophagy-related (ATG)8 family proteins via sequence motifs called LC3-interacting region (LIR) motifs in vertebrates and ...
Trond Lamark, Terje Johansen
exaly   +6 more sources

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Selective autophagy as the basis of autophagy-based degraders

Cell Chemical Biology, 2021
Degrader technologies, which enable the chemical knockdown of disease-causing proteins, are promising for drug discovery. After two decades of research, degraders using the ubiquitin-proteasome system (UPS) are currently in clinical trials. However, the UPS substrates are mainly limited to soluble proteins.
Daiki Takahashi, Hirokazu Arimoto
openaire   +2 more sources

Selective autophagy

Essays in Biochemistry, 2013
During the last decade it has become evident that autophagy is not simply a non-selective bulk degradation pathway for intracellular components. On the contrary, the discovery and characterization of autophagy receptors which target specific cargo for lysosomal degradation by interaction with ATG8 (autophagy-related protein 8)/LC3 (light-chain 3) has ...
Steingrim, Svenning, Terje, Johansen
openaire   +2 more sources