Results 61 to 70 of about 98,515 (154)

The Protective Effects of Κ-Opioid Receptor Stimulation in Hypoxic Pulmonary Hypertension Involve Inhibition of Autophagy Through the AMPK-MTOR Pathway

Cellular Physiology and Biochemistry, 2017
Background/Aims: In a previous study, we showed that κ-opioid receptor stimulation with the selective agonist U50,488H ameliorated hypoxic pulmonary hypertension (HPH).
Yaguang Zhou, Yuanbo Wang, Xu Wang, Xin Tian, Shumiao Zhang, Fan Yang, Haitao Guo, Rong Fan, Na Feng, Min Jia, Xiaoming Gu, Yuemin Wang, Juan Li, Jianming Pei   +13 more
doaj   +1 more source

Chiral polymer modified nanoparticles selectively induce autophagy of cancer cells for tumor ablation

Journal of Nanobiotechnology, 2018
Background Autophagy regulation through exogenous materials has aroused intensive attention to develop treatment protocols according to diverse human diseases.
Long Yuan, Fan Zhang, Xiaowei Qi, Yongjun Yang, Chang Yan, Jun Jiang, Jun Deng   +6 more
doaj   +1 more source

Subversion of selective autophagy for the biogenesis of tombusvirus replication organelles inhibits autophagy.

PLoS Pathogens
Elaborate viral replication organelles (VROs) are formed to support positive-strand RNA virus replication in infected cells. VRO formation requires subversion of intracellular membranes by viral replication proteins.
Yuanrong Kang, Wenwu Lin, Peter D Nagy
doaj   +1 more source

p62-mediated Selective autophagy endows virus-transformed cells with insusceptibility to DNA damage under oxidative stress.

PLoS Pathogens, 2019
DNA damage response (DDR) and selective autophagy both can be activated by reactive oxygen/nitrogen species (ROS/RNS), and both are of paramount importance in cancer development.
Ling Wang, Mary E A Howell, Ayrianna Sparks-Wallace, Caroline Hawkins, Camri A Nicksic, Carissa Kohne, Kenton H Hall, Jonathan P Moorman, Zhi Q Yao, Shunbin Ning   +9 more
doaj   +1 more source

Selective autophagy in type 2 diabetes-associated cognitive dysfunction: Insightful mechanisms and therapies

Pharmacological Research
Type 2 diabetes-associated cognitive dysfunction (TDACD) is an escalating yet underestimated global health challenge, reflecting a complex convergence of metabolic dysregulation and neurodegenerative pathogenesis.
Li Luo, Mengxin Que, Lian Zeng, Xuan Wang, Tianning Sun, Zhiqiang Zhou, Yilin Zhao, Shiyong Li, Ailin Luo   +8 more
doaj   +1 more source

Mechanisms and therapeutic implications of selective autophagy in nonalcoholic fatty liver disease

Journal of Advanced Research
Background: Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease worldwide, whereas there is no approved drug therapy due to its complexity.
Suwei Jin, Yujia Li, Tianji Xia, Yongguang Liu, Shanshan Zhang, Hongbo Hu, Qi Chang, Mingzhu Yan   +7 more
doaj   +1 more source

Controlling inflammation by selective autophagy [PDF]

Cell Death & Differentiation, 2018
Junghyun Lim, Aditya Murthy
openaire   +2 more sources

NBR1-Mediated Selective Autophagy in Plant Development and Stress Responses. [PDF]

Plants (Basel)
Li X, Duan Y, Zhou J, Yu P.
europepmc   +1 more source

Correction: The multifaceted functions of selective autophagy in cancer: molecular basis, consequences, and clinical prospects. [PDF]

Mol Cancer
Jiang M, Zhang K, Li M, Tian Y, Wang T, Rodríguez RA, Lin Z, Meng J, Li C, Wang Z, Wu S, Cai Y, Zhang W, Guo R, Liu Y, Bai Y, Lai G, Zhang C, Bo Z, Wei R.   +19 more
europepmc   +1 more source

Deciphering the Neuroautophagic Interactome: Molecular Circuits Linking Selective Autophagy to Neuropathological Cascades in Neurological Disorders. [PDF]

Int J Biol Sci
Luo P, Travis ZD, Lenahan C, Wu H, Zhang J, Yu J, Xu W.   +6 more
europepmc   +1 more source