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Stereotactic radiation therapy and selective internal radiation therapy for hepatocellular carcinoma
Cancer/Radiothérapie, 2011Recent technological advances allow precise and safe radiation delivery in hepatocellular carcinoma. Stereotactic body radiotherapy is a conformal external beam radiation technique that uses a small number of relatively large fractions to deliver potent doses of radiation therapy to extracranial sites. It requires stringent breathing motion control and
A, Bujold, L A, Dawson
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Selective Internal Radiation therapy
2008Primary and secondary liver tumours are common malignancies associated with unsatisfactory treatment and bad prognosis. Hepatocellular carcinoma (HCC) ranks among the 10 most common cancers worldwide and is the most common primary malignancy of the liver.
A. Al-Nahhas +4 more
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Dose distribution following selective internal radiation therapy
International Journal of Radiation Oncology*Biology*Physics, 1991Selective Internal Radiation Therapy is the intrahepatic arterial injection of microspheres labelled with 90Y. The microspheres lodge in the precapillary circulation of tumor resulting in internal radiation therapy. The activity of the 90Y injected is managed by successive administrations of labelled microspheres and after each injection probing the ...
R A, Fox +5 more
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Selective Internal Radiation Therapy Dosimetry
Future Oncology, 2014Dosimetry is the calculation of radiation energy absorbed by tissue (measured in Grays [Gy]) as a result of exposure to indirect and direct ionizing radiation. The strength of a radioactive source is called its activity, which is defined as the rate at which the isotope decays over time.
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The Evidence for Resection Post-Selective Internal Radiation Therapy
Future Oncology, 2014Selective internal radiation therapy (SIRT) has become a well-established modality for the palliative treatment of primary and metastatic liver tumors. As a consequence of the growing experience with this treatment, research has recently focused on its potential as a component in the management of patients for curative treatment.
Benjamin, Garlipp, Christiane J, Bruns
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British Journal of Hospital Medicine, 2021
Selective internal radiation therapy is a type of brachytherapy used to provide targeted radiotherapy, most commonly to treat primary or metastatic disease within the liver. This review outlines current clinical practice, dosimetric considerations, the pre-treatment workup and safety considerations before treatment.
Emma, Preston, Nadeem, Shaida
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Selective internal radiation therapy is a type of brachytherapy used to provide targeted radiotherapy, most commonly to treat primary or metastatic disease within the liver. This review outlines current clinical practice, dosimetric considerations, the pre-treatment workup and safety considerations before treatment.
Emma, Preston, Nadeem, Shaida
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Optimizing the use of PET with Selective Internal Radiation Therapy
Future Oncology, 2014PET coupled with computed tomography (CT) is indicated for the management of patients undergoing selective internal radiation therapy (SIRT), both as an aid to treatment planning as well as for post-SIRT dosimetry and the assessment of the metabolic response.
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Selective internal radiation therapy: validation of intraoperative dosimetry.
Radiology, 1990In selective internal radiation (SIR) therapy of hepatic metastases, tumor vasculature is preferentially embolized with high-energy beta-emitting yttrium-90-labeled microspheres. To enable accurate estimation of the resultant absorbed radiation doses to tissues, an intraoperative beta detection probe is used to scan the liver surface.
M A, Burton +3 more
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Selective Internal Radiation Therapy
2007The majority of primary and secondary malignant hepatic tumors are not suitable for surgical resection, which makes systemic chemotherapy treatments and/or local ablative therapies important components of intention-to-treat concepts or palliation. Tumor load and type of response determine the efficacy of these therapies.
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Yttrium-90 Selective Internal Radiation Therapy
2017Yttrium-90 Selective internal radiation therapy is a growing part of the field of liver-directed radiation therapy. This technique involves the delivery of radioactive microbeads directly into liver tumors via the blood supply. There are presently two devices available to deliver Y90, with different techniques and clinical considerations for the two ...
D. Thor Johnson, Adam Leon Kesner
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