Results 161 to 170 of about 7,245 (254)

Fluorescent Nanosensor for Indole‐3‐Propionic Acid Detection in Gut Health Monitoring

Advanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.
This work introduces a fluorescent nanosensor system with two optical modalities for detection of indole‐3‐propionic acid (IPA) gut metabolite: (1) blue‐emitting cationic conjugated polyelectrolyte (CP3) and (2) near‐infrared (NIR)‐emitting CP3‐wrapped single‐walled carbon nanotube (SWNT).
Mervin Chun‐Yi Ang, Jonathan Wei Jie Lee, Sayyid Mohaideen, Gabriel Sánchez‐Velázquez, Song Wang, Yangyang Han, Liu Lin, Germaine Yong, Raju Cheerlavancha, Duc Thinh Khong, Jianhong Ching, Sharon Hong Yu Han, Jun Yu Yeo, Lian Xu, Gajendra Pratap Singh, Michael S. Strano   +15 more
wiley   +1 more source

5α-Reductase Isoenzymes: From Neurosteroid Biosynthesis to Neuropsychiatric Outcomes. [PDF]

NeuroSci
Rodriguez-Cerdeira C.
europepmc   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, Volume 13, Issue 32, 9 June 2026.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

Tamoxifen Combined with Hormone Replacement in Women with Thin Endometrium Receiving Frozen-Thawed Embryo Transfer for Promoting Endometrial Growth: A Double-Blinded, Randomized Controlled Trial. [PDF]

Int J Gen Med
Shi Q, Mei J, Yan G, Kong N, Liu J, Shen X, Sun Y, Lu F, Jiang Y, Sun H, Huang C.   +10 more
europepmc   +1 more source

PRMT5/Sohlh2/Sirt1 Signaling Pathway in Vascular Endothelial Cells Modulates Lung Metastasis of Triple‐Negative Breast Cancer

Advanced Science, Volume 13, Issue 31, 4 June 2026.
The cover image shows that vascular endothelial cells play an important role in lung metastasis of TNBC. Endothelial Sohlh2 acts as a gatekeeper against TNBC lung metastasis by limiting endothelial activation and tumor cell passage. PRMT5 reduces Sohlh2 stability, weakening this protective barrier.
Ruihong Zhang, Fengqin Wang, Lanlan Liu, Qi Zhang, Xiaoning Huo, Yanhui Nan, Yanli Dong, Yunling Xiao, Jing Hao   +8 more
wiley   +1 more source

A prospective single-arm pilot study evaluating [F-18]fluoroestradiol dedicated breast PET in invasive lobular carcinoma after neoadjuvant endocrine therapy. [PDF]

Breast Cancer Res
Switalla KM, Onishi N, Jones EF, Lawhn-Heath C, Ray KM, Hathi DK, Carmona-Bozo JC, Metanat P, Lopes AJ, Falade IO, Quirarte A, Gottipati S, Guo R, Molina-Vega J, Pullakhandam K, Bareng TJ, Watkins M, Chien AJ, Joe BN, Esserman LJ, Hylton N, Mukhtar RA.   +21 more
europepmc   +1 more source

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

Advanced Science, Volume 13, Issue 33, 15 June 2026.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu, Yujia Zhou, Zihan Zhang, Rong Ma, Luyi Ruan, Liqing Miao, Boxin Zhang, Huihui Ji, Tianfeng Chen, Xueqiong Zhu   +9 more
wiley   +1 more source

ZMIZ1 and estrogen receptor α form an essential partnership in endometrial biology. [PDF]

J Clin Invest
Rahman MS, So KA, Jeong JW.
europepmc   +1 more source

Cholesterol and Cholesterol‐Derived Molecules Differentially Modulate Neuronal Kv7.2/7.3 Channels

Archiv der Pharmazie, Volume 359, Issue 6, June 2026.
Cholesterol, steroid hormones, and cholesterol‐based imidazolium salts (CHIMs) inhibit Kv7.2/Kv7.3 channels. Notably, NBD‐tagged CHIM‐L enhances currents. These findings demonstrate that both chemical modifications and linker length differentially modulate Kv7 activity, revealing variant‐specific sensitivities and potential pharmacological targets for ...
Elif Karabatak, Ronewa Nematswerani, Vivian Meiritz, Nicole Rychlik, Guiscard Seebohm, Frank Glorius, Thomas Budde   +6 more
wiley   +1 more source

The interaction between inflammation and estrogen in adenomyosis : from molecular mechanisms to therapeutic strategies. [PDF]

Semin Immunopathol
Li F, Wang HJ, Zhang Y, Nan FJ, Xu L, Liu ZY, Shi W.   +6 more
europepmc   +1 more source