Results 191 to 200 of about 7,245 (254)

Metabolic Signatures and Diagnostic Prediction Models for Coronary Artery Disease and Type 2 Diabetes Mellitus: Insights From an Exploratory Study

iNew Medicine, Volume 2, Issue 2, June 2026.
Metabolomic & lipidomic analysis reveals metabolic overlap between CAD & T2DM, highlighting 7 key metabolites as potential biomarkers. A predictive model based on these achieves high accuracy, potentially advancing precision medicine & metabolic insights.
Zhihua Wang, Meiming Su, Ying Li, Yapei Li, Shuo Chen, Ting Peng, Hans Strijdom, Jiangang Wang, Jianping Weng, Suowen Xu   +9 more
wiley   +1 more source

Nuclear and membrane-bound hormone receptors in glioblastoma: Expression, functionality, and therapeutic implications. [PDF]

Neurooncol Adv
Gantner A, Dubois-Pot-Schneider H, Dumond H.   +2 more
europepmc   +1 more source

Vacuolization as a Novel Approach to Cancer Therapy

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak, Noor Hussein, Veronica Piedra, Saloni Malla, Chandrabose Karthikeyan, Haneen Amawi, Harish Rajak, Charles R. Ashby Jr., R. Jayachandra Babu, Amit K. Tiwari   +9 more
wiley   +1 more source

Review of hormonal replacement therapy options for the treatments of menopausal symptoms. [PDF]

Korean J Fam Med
Edelweishia M, Christoper A, Theresia E, Angelia V.   +3 more
europepmc   +1 more source

CD133 Shapes Extracellular Vesicle Cargo and Angiogenic Function in Basal‐Like Triple‐Negative Breast Cancer

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Extracellular vesicles (EVs) are central mediators of tumour‐stroma communication, yet the mechanisms governing their biogenesis and functional cargo remain poorly understood. Here, we identify CD133 (Prominin‐1), selectively expressed in basal‐like triple‐negative breast cancer (BL‐TNBC) cells, acts as a key organizer of EV production and ...
Mireia Gomez‐Duro, Ptissam Bergam, Sara Sanchez‐Redondo, Florent Dingli, Alix Zhou, Alain Joliot, Mengliang Ye, Marta Hergueta‐Redondo, Lucas Alves Tavares, Damarys Loew, Thierry Dubois, Lorena Martin‐Jaular, Hector Peinado, Graça Raposo, Gisela D'Angelo   +14 more
wiley   +1 more source

Sex differences in immune cells: mechanistic perspectives and clinical correlates in physiology and disease. [PDF]

Front Immunol
Liao X, Wu D, Gao J, Xie F, Li Z, Wang M, Wang K, Gao Y, Li Q, Gao W.   +9 more
europepmc   +1 more source

Menopause and Plantar Heel Pain: Findings From a Series of Focus Groups Exploring Lived Experience

Journal of Foot and Ankle Research, Volume 19, Issue 2, June 2026.
ABSTRACT Background Plantar heel pain (PHP) is a debilitating problem disproportionately affecting women between the age of 40 and 60 at twice the rate of men, coinciding with perimenopause and menopause. Whether a causative relationship exists is uncertain, but their concurrence presents challenges for both patients and healthcare providers.
Matthew Douglas‐Harris, Richard Wilkins, Jayasree Ramaskandhan, Jagjit Mankelow, Helen Branthwaite   +4 more
wiley   +1 more source

Molecular Mechanisms of Dysregulated LH and FSH Secretion in Human Reproductive Failure. [PDF]

Biomedicines
Zikopoulos A, Moustakli E, Potiris A, Paraschos VS, Katopodis P, Machairoudias P, Antsaklis P, Kathopoulis N, Anagnostaki I, Stavros S.   +9 more
europepmc   +1 more source

The estrogen-progestogen-oxidative stress network in uterine fibroids: mechanistic insights and therapeutic opportunities. [PDF]

Redox Rep
Wang S, You W, Ding D, Liu F, Han F, Tang L.   +5 more
europepmc   +1 more source