Results 11 to 20 of about 49,570 (201)

Selective serotonin reuptake inhibitors and Alzheimer’s disease

Neural Regeneration Research, 2020
Given the failure to develop disease-modifying therapies for Alzheimer’s disease (AD), strategies aiming at preventing or delaying the onset of the disease are being prioritized. While the debate regarding whether depression is an etiological risk factor
Bernadette Mdawar, Elias Ghossoub, Rita Khoury   +2 more
doaj   +2 more sources

Selective serotonin reuptake inhibitors for fibromyalgia syndrome

São Paulo Medical Journal, 2015
BACKGROUND: Fibromyalgia is a clinically well-defined chronic condition with a biopsychosocial aetiology. Fibromyalgia is characterized by chronic widespread musculoskeletal pain, sleep problems, cognitive dysfunction, and fatigue. Patients often report
Brian Walitt, Gerard Urrútia, María Betina Nishishinya, Sarah E. Cantrell, Winfried Häuser   +4 more
doaj   +2 more sources

Rapid response to selective serotonin reuptake inhibitors in post-COVID depression

European Neuropsychopharmacology, 2021
The spreading of the Severe Acute Respiratory Syndrome Coronavirus (COVID-19) pandemic could be associated with psychiatric implications. After COVID-19, depression was reported in 40% of patients at one-, three-, and six-months follow-up.
M. Mazza, R. Zanardi, M. Palladini, P. Rovere-Querini, F. Benedetti   +4 more
semanticscholar   +1 more source

The possible immunoregulatory and anti-inflammatory effects of selective serotonin reuptake inhibitors in coronavirus disease patients

Medical Hypotheses, 2020
While researchers are struggling to develop a vaccine for coronavirus disease, it is important to evolve effective therapeutic strategies to save lives. The majority of coronavirus disease deaths are due to pneumonia.
M. Hamed, R. Hagag
semanticscholar   +1 more source

Case-Control Study Examining the Association between Selective Serotonin Reuptake Inhibitors Use and Hepatocellular Carcinoma

Frontiers in Pharmacology, 2017
Objectives: The purpose of the study was to assess the relationship between selective serotonin reuptake inhibitors use and hepatocellular carcinoma in Taiwan.Methods: Using the database of the Taiwan National Health Insurance Program, we conducted a ...
Shih-Wei Lai, Shih-Wei Lai, Kuan-Fu Liao, Kuan-Fu Liao, Cheng-Li Lin, Cheng-Li Lin, Hsien-Feng Lin, Hsien-Feng Lin   +7 more
doaj   +1 more source

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors

Clinical pharmacology and therapy, 2015
Selective serotonin reuptake inhibitors (SSRIs) are primary treatment options for major depressive and anxiety disorders. CYP2D6 and CYP2C19 polymorphisms can influence the metabolism of SSRIs, thereby affecting drug efficacy and safety.
J. Hicks, J. Bishop, K. Sangkuhl, Daniel J. Müller, Yuan Ji, SG Leckband, J. S. Leeder, Rebecca L. Graham, DL Chiulli, A. Llerena, T. Skaar, S. Scott, J. Stingl, T. Klein, K. Caudle, A. Gaedigk   +15 more
semanticscholar   +1 more source

Optimal dose of selective serotonin reuptake inhibitors, venlafaxine, and mirtazapine in major depression: a systematic review and dose-response meta-analysis

Lancet psychiatry, 2019
Summary Background Depression is the single largest contributor to non-fatal health loss worldwide. Second-generation antidepressants are the first-line option for pharmacological management of depression.
T. Furukawa, A. Cipriani, P. Cowen, S. Leucht, M. Egger, G. Salanti   +5 more
semanticscholar   +1 more source

Oral selective serotonin reuptake inhibitors activate vagus nerve dependent gut-brain signalling

Scientific Reports, 2019
The vagus nerve can transmit signals to the brain resulting in a reduction in depressive behavior as evidenced by the long-term beneficial effects of electrical stimulation of the vagus in patients with intractable depression.
Karen‐Anne McVey Neufeld, J. Bienenstock, Aadil Bharwani, K. Champagne-Jorgensen, Y. Mao, Christine L West, Yunpeng Liu, M. Surette, W. Kunze, P. Forsythe   +9 more
semanticscholar   +1 more source

The genetics of selective serotonin reuptake inhibitors

Pharmacology & Therapeutics, 2012
Selective serotonin reuptake inhibitors (SSRIs) are among the most widely prescribed drugs in psychiatry. Based on the fact that SSRIs increase extracellular monoamine levels in the brain, the monoamine hypothesis of depression was introduced, postulating that depression is associated with too low serotonin, dopamine and noradrenaline levels.
Kroeze, Y.L., Kroeze, Y.L., Zhou, Huiqing, Homberg, J.R.   +3 more
openaire   +3 more sources

Selective Serotonin Reuptake Inhibitors Aggravate Depression-Associated Dry Eye Via Activating the NF-κB Pathway.

Investigative Ophthalmology and Visual Science, 2019
Purpose Our study aimed to evaluate the side effects of selective serotonin reuptake inhibitors (SSRIs) on the ocular surface. Methods Twenty patients with depression and dry eye disease (DED) were randomly picked to receive SSRI treatment, whereas ...
Xiaozhao Zhang, Yue Yin, Ling Yue, L. Gong   +3 more
semanticscholar   +1 more source