Results 31 to 40 of about 49,570 (201)

Pharmacokinetics and Pharmacodynamics: A Comprehensive Analysis of the Absorption, Distribution, Metabolism, and Excretion of Psychiatric Drugs

Pharmaceuticals
The two main classifications of antidepressant medications are selective norepinephrine reuptake inhibitors (SNRIs) and selective serotonin reuptake inhibitors (SSRIs).
Zainab Zakaraya, Mohammad Abu Assab, Lina N. Tamimi, Nida Karameh, Mohammad Hailat, Laila Al-Omari, Wael Abu Dayyih, Omar Alasasfeh, Mohammad Awad, Riad Awad   +9 more
doaj   +1 more source

Data on the impact of SSRIs and depression symptoms on the neural activities in obsessive–compulsive disorder at rest

Data in Brief, 2016
The data provided here related to our research article (Chen et al., 2016) [1]. We provide whole-brain intrinsic functional connectivity patterns in obsessive–compulsive disorder at resting-state [1].
Yunhui Chen, Michal Juhas, Andrew J Greenshaw, Qiang Hu, Xin Meng, Hongsheng Cui, Yongzhuo Ding, Lu Kang, Yubo Zhang, Yuhua Wang, Guangcheng Cui, Ping Li   +11 more
doaj   +1 more source

Endophenotypes and serotonergic polymorphisms associated with treatment response in obsessive-compulsive disorder

Clinics, 2012
OBJECTIVES: Approximately 40-60% of obsessive-compulsive disorder patients are nonresponsive to serotonin reuptake inhibitors. Genetic markers associated with treatment response remain largely unknown.
Fábio M. Corregiari, Márcio Bernik, Quirino Cordeiro, Homero Vallada   +3 more
doaj   +1 more source

Extrapyramidal symptoms and antidepressants – A systematic review

Telangana Journal of Psychiatry
Selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, and tricyclic antidepressants have all been implicated, albeit to varying extents, in precipitating extrapyramidal symptoms.
Ankit Halder, Disha Maity, Satrajit Ghosal, Ashwini Lad   +3 more
doaj   +1 more source

Tratamento farmacológico do transtorno obsessivo-compulsivo

Brazilian Journal of Psychiatry, 2001
The pharmacotherapy for obsessive-compulsive disorder (OCD) has started with clomipramine, a potent non-selective serotonin reuptake inhibitor. Newer drugs that selectively inhibit serotonin reuptake (SSRIs) such as fluvoxamine, fluoxetine, paroxetine ...
Carla Marques
doaj   +1 more source

Consistent superiority of selective serotonin reuptake inhibitors over placebo in reducing depressed mood in patients with major depression

Molecular Psychiatry, 2015
The recent questioning of the antidepressant effect of selective serotonin reuptake inhibitors (SSRIs) is partly based on the observation that approximately half of company-sponsored trials have failed to reveal a significant difference between active ...
F. Hieronymus, J. Emilsson, Staffan Nilsson, Elias Eriksson   +3 more
semanticscholar   +1 more source

TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics

Molecular Psychiatry, 2016
Millions of patients suffer from major depressive disorder (MDD), but many do not respond to selective serotonin reuptake inhibitor (SSRI) therapy. We used a pharmacometabolomics-informed pharmacogenomics research strategy to identify genes associated ...
Meenal Gupta, Drew Neavin, Duan Liu, J. Biernacka, D. Hall‐Flavin, W. Bobo, M. Frye, M. Skime, G. Jenkins, A. Batzler, K. Kalari, W. Matson, Swati S. Bhasin, Hongjie Zhu, T. Mushiroda, Y. Nakamura, M. Kubo, Liewei Wang, R. Kaddurah-Daouk, R. Weinshilboum   +19 more
semanticscholar   +1 more source

Selective Serotonin Reuptake Inhibitors

, 2017
Selective serotonin reuptake inhibitors (SSRIs) are used primarily for treatment of depression and anxiety. Their effectiveness in pain management is limited and inconsistent.
Robert M. Chow, Mohammed Issa
  +4 more sources

Efficacy and Safety of Antidepressants for the Treatment of Irritable Bowel Syndrome: A Meta-Analysis.

PLoS ONE, 2015
AimThe aim of this meta-analysis was to analyze the efficacy and safety of antidepressants for the treatment of irritable bowel syndrome.MethodsWe searched MEDLINE, EMBASE, Scopus and The Cochrane Library for randomized controlled trials investigating ...
Chen Xie, Yurong Tang, Yunfeng Wang, Ting Yu, Yun Wang, Liuqin Jiang, Lin Lin   +6 more
doaj   +1 more source

Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database

BMC Medicine, 2018
Background Antidepressants are one of the most commonly prescribed medications in young and middle-aged adults, but there is relatively little information on their safety across a range of adverse outcomes in this age group.
Carol Coupland, Trevor Hill, Richard Morriss, Michael Moore, Antony Arthur, Julia Hippisley-Cox   +5 more
doaj   +1 more source