Development and validation of a selenium metabolism regulators associated prognostic model for hepatocellular carcinoma [PDF]
BMC Cancer, 2023 Background Selenium metabolism has been implicated in human health. This study aimed to identify a selenium metabolism regulator-based prognostic signature for hepatocellular carcinoma (HCC) and validate the role of INMT in HCC.
Huishan Sun +10 more
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The role of selenium metabolism and selenoproteins in cartilage homeostasis and arthropathies [PDF]
Experimental and Molecular Medicine, 2020 Joint health: the rare micronutrient selenium may be crucial Selenium, a micronutrient found in brazil nuts, shiitake mushrooms, and most meats, may aid in treating joint diseases, including the most common form of arthritis, osteoarthritis (OA).
Donghyun Kang +6 more
doaj +2 more sources
WRKY transcription factors govern selenium metabolism in Broussonetia papyrifera: genome-wide identification, expression profiling, and regulatory network analysis [PDF]
BMC Plant BiologyBackground Broussonetia papyrifera, a novel forage tree species, exhibits a notable ability to accumulate selenium, making it a viable option for selenium enrichment feed.
Huimin He +7 more
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Metabolism of Selenium, Selenocysteine, and Selenoproteins in Ferroptosis in Solid Tumor Cancers
Biomolecules, 2022 A potential target of precision nutrition in cancer therapeutics is the micronutrient selenium (Se). Se is metabolized and incorporated as the amino acid selenocysteine (Sec) into 25 human selenoproteins, including glutathione peroxidases (GPXs) and ...
Briana K. Shimada +3 more
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Identification and validation of selenium metabolism-related genes in lung adenocarcinoma prognosis using bioinformatics analysis [PDF]
Frontiers in GeneticsBackgroundThe disruption of selenium metabolism has been associated with tumor progression. However, the prognostic significance and underlying molecular mechanisms of selenium metabolism in lung adenocarcinoma (LUAD) remain inadequately understood. This
Yun Chen +6 more
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SEXUAL DIMORPHISM IN SELENIUM METABOLISM AND SELENOPROTEINS. [PDF]
Free Radic Biol Med, 2018 Sexual dimorphism, the condition in which males and females in a species differ beyond the morphology of sex organs, delineates critical aspects of the biology of higher eukaryotes, including selenium metabolism. While sex differences in selenium biology have been described by several laboratories, delineation of the effects of sex in selenium function
Seale LA, Ogawa-Wong AN, Berry MJ.
europepmc +4 more sources
The Integral Boosting Effect of Selenium on the Secondary Metabolism of Higher Plants
Plants, 2022 Selenium is a micronutrient with a wide range of functions in animals, including humans, and in microorganisms such as microalgae. However, its role in plant metabolism remains ambiguous.
Liubov Skrypnik +7 more
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Selenium in the Environment, Metabolism and Involvement in Body Functions
Molecules, 2013 Selenium (Se34 79) is a metalloid which is close to sulfur (S) in terms of properties. The Se concentration in soil varies with type, texture and organic matter content of the soil and with rainfall.
Isabelle Dufrasne +3 more
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Selenium metabolism heterogeneity in pan-cancer: insights from bulk and single-cell RNA sequencing [PDF]
Journal of Cancer Research and Clinical Oncology, 2023 Heng Xu, Yang Shu, Hai-Ning Chen
exaly +2 more sources
Ecotoxicology and Environmental Safety, 2023 Selenium plays a vital role in cancer prevention, antioxidation, and the growth of humans and other vertebrates. Excessive selenium can cause liver injury and metabolic disorders, which can lead to hepatic disease, but few studies have shown the effects ...
Yuejie Zhu +7 more
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