Development and validation of a selenium metabolism regulators associated prognostic model for hepatocellular carcinoma [PDF]
BMC Cancer, 2023 Background Selenium metabolism has been implicated in human health. This study aimed to identify a selenium metabolism regulator-based prognostic signature for hepatocellular carcinoma (HCC) and validate the role of INMT in HCC.
Huishan Sun +10 more
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The role of selenium metabolism and selenoproteins in cartilage homeostasis and arthropathies [PDF]
Experimental and Molecular Medicine, 2020 Joint health: the rare micronutrient selenium may be crucial Selenium, a micronutrient found in brazil nuts, shiitake mushrooms, and most meats, may aid in treating joint diseases, including the most common form of arthritis, osteoarthritis (OA).
Donghyun Kang +6 more
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WRKY transcription factors govern selenium metabolism in Broussonetia papyrifera: genome-wide identification, expression profiling, and regulatory network analysis [PDF]
BMC Plant BiologyBackground Broussonetia papyrifera, a novel forage tree species, exhibits a notable ability to accumulate selenium, making it a viable option for selenium enrichment feed.
Huimin He +7 more
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Metabolism of Selenium, Selenocysteine, and Selenoproteins in Ferroptosis in Solid Tumor Cancers
Biomolecules, 2022 A potential target of precision nutrition in cancer therapeutics is the micronutrient selenium (Se). Se is metabolized and incorporated as the amino acid selenocysteine (Sec) into 25 human selenoproteins, including glutathione peroxidases (GPXs) and ...
Briana K. Shimada +3 more
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Identification and validation of selenium metabolism-related genes in lung adenocarcinoma prognosis using bioinformatics analysis [PDF]
Frontiers in GeneticsBackgroundThe disruption of selenium metabolism has been associated with tumor progression. However, the prognostic significance and underlying molecular mechanisms of selenium metabolism in lung adenocarcinoma (LUAD) remain inadequately understood. This
Yun Chen +6 more
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Integrated transcriptomics and metabolomics reveal key metabolic pathway responses in Mentha Piperita L. under selenite stress [PDF]
BMC Plant BiologySelenium (Se) is a beneficial micronutrient that, at optimal concentrations, supports plant growth, stress resistance, and secondary metabolism. However, its regulatory effects are highly dose-dependent.
Guangai Deng +4 more
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Ecotoxicology and Environmental Safety, 2023 Selenium plays a vital role in cancer prevention, antioxidation, and the growth of humans and other vertebrates. Excessive selenium can cause liver injury and metabolic disorders, which can lead to hepatic disease, but few studies have shown the effects ...
Yuejie Zhu +7 more
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Microbiology Spectrum, 2023 Selenium (Se) is a micronutrient in most eukaryotes, and Se-enriched yeast is the most common selenium supplement. However, selenium metabolism and transport in yeast have remained unclear, greatly hindering the application of this element.
Ao Gong +4 more
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Inorganic Selenium Transformation into Organic Selenium by Monascus purpureus
Foods, 2023 Selenium (Se) is a trace element that plays a crucial role in metabolism; a lack of selenium reduces the body’s resistance and immunity, as well as causes other physiological problems.
Nan Sun +8 more
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Thyroid hormones regulate selenoprotein expression and selenium status in mice. [PDF]
PLoS ONE, 2010 Impaired expression of selenium-containing proteins leads to perturbed thyroid hormone (TH) levels, indicating the central importance of selenium for TH homeostasis.
Jens Mittag +4 more
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