Selex aptamer technique - Open Access .click

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SELEX Modifications and Bioanalytical Techniques for Aptamer–Target Binding Characterization

Critical Reviews in Analytical Chemistry, 2016
The quest to improve the detection of biomolecules and cells in health and life sciences has led to the discovery and characterization of various affinity bioprobes. Libraries of synthetic oligonucleotides (ssDNA/ssRNA) with randomized sequences are employed during Systematic Evolution of Ligands by Exponential Enrichment (SELEX) to select highly ...
Tan, S. +5 more
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Electrochemical SELEX Technique for the Selection of DNA Aptamers against the Small Molecule 11-Deoxycortisol

ACS Applied Bio Materials, 2019
Aptamers have received considerable attention due to their numerous advantages as biorecognition receptors. However, the tediousness and high cost of the conventional selection process of aptamers remain major challenges that limit their widespread use.
Shimaa Eissa +3 more
openaire +3 more sources

An improved SELEX technique for selection of DNA aptamers binding to M-type 11 of Streptococcus pyogenes

Methods, 2016
Streptococcus pyogenes is a clinically important pathogen consisting of various serotypes determined by different M proteins expressed on the cell surface. The M type is therefore a useful marker to monitor the spread of invasive S. pyogenes in a population.
Camille L.A. Hamula +5 more
openaire +3 more sources

Electrochemiluminescence-Based Lateral Flow Assay for Detection of Cardiac Troponin T Using Aptamers Developed through a Modified SELEX Technique