Results 21 to 30 of about 5,227 (180)

Aptamers and Cancer

open access: yesAsian Pacific Journal of Cancer Biology, 2016
Oligonucleotides Aptamers are single strands of DNA and RNA with the length of 20-100 nucleotides or peptides and unique three dimensional structure that is affected by nucleotide sequence. The structure exclusively influences aptamers’ bindings with its
Nasrin Yazdanpanahi   +2 more
doaj   +3 more sources

Combined aptamer and transcriptome sequencing of single cells. [PDF]

open access: yes, 2018
The transcriptome and proteome encode distinct information that is important for characterizing heterogeneous biological systems. We demonstrate a method to simultaneously characterize the transcriptomes and proteomes of single cells at high throughput ...
Abate, Adam R   +3 more
core   +2 more sources

Conjugate-SELEX: A High-throughput Screening of Thioaptamer-liposomal Nanoparticle Conjugates for Targeted Intracellular Delivery of Anticancer Drugs

open access: yesMolecular Therapy: Nucleic Acids, 2016
Patients with advanced head and neck squamous cell carcinoma receiving chemotherapy have a poor prognosis partly due to normal tissue toxicity; therefore, development of a tumor-targeted drug delivery platform to minimize collateral toxicity is a goal of
Qingshan Mu   +10 more
doaj   +1 more source

Development of DNA aptamer selection approach based on membrane ultrafiltration of aptamer/target complex

open access: yesActa Biomedica Scientifica, 2022
Background. Aptamers are small single-stranded DNA or RNA molecules that have an affinity for a specific target molecule. The main method of aptamers construction is the technology of systematic evolution of ligands with exponential enrichment (SELEX ...
I. S. Solovarov   +4 more
doaj   +1 more source

A New Design for the Fixed Primer Regions in an Oligonucleotide Library for SELEX Aptamer Screening

open access: yesFrontiers in Chemistry, 2020
Single-stranded DNA or RNA oligonucleotides, often called aptamers, can bind to a molecular target with both high affinity and selectivity due to their distinct three-dimensional structures.
Bin Wang
doaj   +1 more source

Selection of DNA aptamer and its application as an electrical biosensor for Zika virus detection in human serum

open access: yesNano Convergence, 2022
Zika virus is a highly infectious virus that is part of the flavivirus group. Precise diagnosis of the Zika virus is significant issue for controlling a global pandemic after the COVID-19 era.
Goeun Park   +5 more
doaj   +1 more source

Selection Of A Novel Aptamer Against Vitronectin Using Capillary Electrophoresis And Next Generation Sequencing [PDF]

open access: yes, 2016
Breast cancer (BC) results in ≃40,000 deaths each year in the United States and even among survivors treatment of the disease may have devastating consequences, including increased risk for heart disease and cognitive impairment resulting from the toxic ...
Boyacioglu, O.   +8 more
core   +3 more sources

In vitro Selection of DNA Aptamers and Fluorescence-Based Recognition for Rapid Detection Listeria monocytogenes

open access: yesJournal of Integrative Agriculture, 2014
Aptamers are specific nucleic acid sequences that can bind to a wide range of nucleic acid and non-nucleic acid targets with high affinity and specificity.
Guo-qing LIU   +7 more
doaj   +1 more source

A blue light receptor that mediates RNA binding and translational regulation [PDF]

open access: yes, 2019
Sensory photoreceptor proteins underpin light-dependent adaptations in nature and enable the optogenetic control of organismal behavior and physiology.
Bittl, Robert   +9 more
core   +1 more source

Aptamer based diagnosis of crimean-congo hemorrhagic fever from clinical specimens

open access: yesScientific Reports, 2021
Crimean-Congo hemorrhagic fever (CCHF) is an acute viral zoonotic disease. The widespread geographic distribution of the disease and the increase in the incidence of the disease from new regions, placed CCHF in a list of public health emergency contexts.
Tahmineh Jalali   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy