Results 31 to 40 of about 5,227 (180)
Aptamer-Based Optical and Electrochemical Sensors: A Review
Chemosensors, 2023 There is a pressing need to identify recent directions in the field of aptamer-based sensing. DNA aptamers that are synthetically generated by in vitro selection mechanisms using the SELEX technique are single-stranded oligonucleotides which are selected
Sidra Farid +3 more
doaj +1 more source
Selection and targeting of EpCAM protein by ssDNA aptamer. [PDF]
PLoS ONE, 2017 Aptamers are molecules that reveal highly complex and refined molecular recognition properties. These molecules are capable of binding with high affinity and selectivity to targets, ranging from small molecules to whole living cells.
Walhan Alshaer +11 more
doaj +1 more source
Microbiology Spectrum, 2023 Infectious bronchitis virus (IBV) is a coronavirus responsible for major health problems in the poultry industry. New virus strains continue to appear, causing large economic losses. To develop a rapid and accurate new quantitative assay for diagnosis of
Issam Hmila +3 more
doaj +1 more source
Electrochemical aptasensor for human osteopontin detection using a DNA aptamer selected by SELEX [PDF]
, 2017 A DNA aptamer with affinity and specificity for human osteopontin (OPN), a potential breast cancer biomarker, was selected using the SELEX process, considering its homology rate and the stability of its secondary structures.
Ahmed +73 more
core +1 more source
Probing the limits of aptamer affinity with a microfluidic SELEX platform. [PDF]
PLoS ONE, 2011 Nucleic acid-based aptamers offer many potential advantages relative to antibodies and other protein-based affinity reagents, including facile chemical synthesis, reversible folding, improved thermal stability and lower cost.
Kareem M Ahmad +5 more
doaj +1 more source
Viruses, 2022 Zika virus became a major public health problem in early 2015, when cases of Guillain–Barré syndrome and microcephaly were associated with viral infection.
Liliane Monteiro de Morais +7 more
doaj +1 more source
Current and Potential Developments of Cortisol Aptasensing towards Point-of-Care Diagnostics (POTC) [PDF]
, 2017 Anxiety is a psychological problem that often emerges during the normal course of human life. The detection of anxiety often involves a physical exam and a self-reporting questionnaire. However, these approaches have limitations, as the data might lack
A. Rahim, Ruslinda +6 more
core +3 more sources
Aptamer-based cocaine assay using a nanohybrid composed of ZnS/Ag2Se quantum dots, graphene oxide and gold nanoparticles as a fluorescent probe [PDF]
, 2020 Authors report on a new fluoro-graphene-plasmonic nanohybrid aptamer-based fluorescent nanoprobe for cocaine. To construct the nanoprobe, newly synthesized glutathione-capped ZnS/Ag 2Se quantum dots (QDs) were first conjugated to graphene oxide (GO) to ...
Abdolvand, Amin +4 more
core +2 more sources
Tuning Polyacrylate Composition to Recognize and Modulate Fluorescent Proteins
Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.Random hetero oligomers (RHOs) of defined compositions are synthesized and fractionated to identify the chemical design criteria (charge, length, hydrophobicity) required to achieve nanomolar binding to green fluorescent protein, resulting in >100% fluorescence increases.
Darwin C. Gomez +12 more
wiley +2 more sources
Aptamers and Their Significant Role in Cancer Therapy and Diagnosis
Biomedicines, 2015 Aptamers are nucleic acid/peptide molecules that can be generated by a sophisticated, well-established technique known as Systematic Evolution of Ligands by EXponential enrichment (SELEX).
Joy Sebastian Prakash +1 more
doaj +1 more source