Results 61 to 70 of about 5,227 (180)
Aptamer Microarrays-Current Status and Future Prospects [PDF]
, 2015 Microarray technologies are state of the art in biological research, which requires fast genome, proteome and transcriptome analysis technologies. Often antibodies are applied in protein microarrays as proteomic tools.
Stahl, Frank +2 more
core +3 more sources
Progress in RNA‐Targeted Therapeutics for Human Diseases
MedComm, Volume 7, Issue 2, February 2026.RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang +10 more
wiley +1 more source
Aptamers: A new approach to detection of target molecules [PDF]
فصلنامه ابن سینا, 2016 Background: For more than three decades, antibodies were recognized as the most common class of diagnostic molecules with a wide range of applications, until aptamers became as widespread as antibodies.
M ebrahimi, R Lalavi
doaj
Nanogravimetric and Optical Characterizations of Thrombin Interaction with a Self-Assembled Thiolated Aptamer [PDF]
, 2016 Efficient biorecognition of thrombin (TB), a serine protease with crucial role in physiological and pathological blood coagulation, is a hot topic in medical diagnostics.
Borbone, Nicola +8 more
core +2 more sources
Aptamers in oncology: a diagnostic perspective [PDF]
, 2008 Nucleic acid sequences can produce a wide variety of three-dimensional conformations. Some of these structural forms are able to interact with proteins and small molecules with high affinity and specificity.
Khan, Huma, Missailidis, Sotiris
core
Efficient isolation and elution of cellular proteins using aptamer-mediated protein precipitation assay [PDF]
Protein precipitation is one of the most widely used methods for antigen detection and purification in biological research. We developed a reproducible aptamer-mediated magnetic protein precipitation method that is able to efficiently capture, purify and
Han, D, Kim, K, Lee, S, Ryu, S
core +1 more source
G-quadruplex DNA aptamers and their ligands: Structure, function and application [PDF]
, 2012 Highly specific and tight-binding nucleic acid aptamers have been selected against a variety of molecular targets for over 20 years. A significant proportion of these oligonucleotides display G-quadruplex structures, particularly for DNA aptamers, that ...
Shum, KT, Tanner, JA, Tucker, WO
core +1 more source
Advanced Healthcare Materials, Volume 15, Issue 4, 26 January 2026.Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao +2 more
wiley +1 more source
Fluorescence-based strategies to investigate the structure and dynamics of aptamer-ligand complexes [PDF]
, 2016 This work was funded by the Scottish Universities Physics Alliance (SUPA), the University of St Andrews, the Engineering and Physical Sciences ResearchCouncil (EPSRC), the Canadian Institutes of Health Research (CIHR).
Lafontaine, Daniel A +2 more
core +1 more source
Advanced Sensor Research, Volume 5, Issue 1, January 2026.This paper reviews the state of the art and recent developments in thin‐film biosensors for the detection of neurotransmitters, small molecules, and biomarkers within flexible, implantable bioelectronic systems. It covers the main sensing modalities, including electrochemical, plasmonic, acoustic, and magnetic, alongside their materials, transduction ...
Massimo Mariello
wiley +1 more source