Results 81 to 90 of about 5,227 (180)

Ligase‐Catalyzed Transcription and Reverse Transcription of XNA by T3 DNA Ligase

Current Protocols, Volume 6, Issue 1, January 2026.
Abstract The growing utility of xeno‐nucleic acids (XNAs) lies in their ability to extend the reach of genetic chemistry beyond the limits imposed by natural polymers. XNAs, with their diverse chemical backbones, resist enzymatic degradation and yet retain the capacity for sequence‐defined information, and have found broad applications in biotechnology.
Natalie Khamissi, Luca Rustico, Ryan Hili   +2 more
wiley   +1 more source

Selection and Application of Specific Nucleic Acid Aptamers for the Detection of Pseudomonas aeruginosa [PDF]

Shipin Kexue
For rapid and sensitive detection of pathogenic bacterium Pseudomonas aeruginosa, the whole-cell systematic evolution of ligands by exponential enrichment (SELEX) technique was used to select single-stranded DNA (ssDNA) aptamers specific for P ...
LI Xu, CHENG Yangyang, YANG Kai, LIU Benkang, LI Cheng
doaj   +1 more source

Recent Developments in Capillary and Microchip Electroseparations of Peptides (2023–mid 2025)

ELECTROPHORESIS, Volume 47, Issue 1, Page 106-136, January 2026.
ABSTRACT This review presents a comprehensive overview of the developments and applications of high‐performance capillary and microchip electromigration methods (zone electrophoresis in a free solution or in sieving media, isotachophoresis, isoelectric focusing, affinity electrophoresis, electrokinetic chromatography, and electrochromatography) for ...
Václav Kašička
wiley   +1 more source

Exosome‐Based Cartilage‐Targeted Delivery System: Strategies and Applications

Small Science, Volume 6, Issue 1, January 2026.
Construction strategies and applications of cartilage‐targeting exosomes. With the ageing of the global population, cartilage‐related diseases, such as osteoarthritis (OA) and intervertebral disc degeneration (IVDD), have increasingly become significant social problems threatening human health. Therefore, targeted therapy for cartilage is becoming more
Yao Wang, Bo Chen, Haodong Zhu, Zhenyu Sun   +3 more
wiley   +1 more source

Prediction of aptamer-protein interacting pairs using an ensemble classifier in combination with various protein sequence attributes [PDF]

, 2016
The ranked feature list given by the Relief algorithm. Within the list, a feature with a smaller index indicates that it is more important for aptamer-protein interacting pair prediction.
Chengjin Zhang, Lina Zhang, Qing Song, Rui Gao, Runtao Yang   +4 more
core   +2 more sources

Genomic RNA folding mediates assembly of human parechovirus [PDF]

, 2017
Assembly of the major viral pathogens of the Picornaviridae family is poorly understood. Human parechovirus 1 is an example of such viruses that contains 60 short regions of ordered RNA density making identical contacts with the protein shell.
Butcher, Sarah Jane, Cockburn, Joe, Dykeman, Eric C, Ora, Ari, Shakeel, Shabih, Stockley, Peter G, Twarock, Reidun, White, Simon J   +7 more
core   +4 more sources

Screening of specific nucleic acid aptamers binding tumor markers in the serum of the lung cancer patients and identification of their activities

Tumor Biology, 2017
Lung cancer is by far the leading cause of cancer death in the world. Despite the improvements in diagnostic methods, the status of early detection was not achieved. So, a new diagnostic method is needed.
Kun Li, Chen-Lin Xiu, Li-Ming Gao, Hua-Gang Liang, Shu-Feng Xu, Ming Shi, Jian Li, Zhi -Wei Liu   +7 more
doaj   +1 more source

A novel approach to latent fingermark detection using aptamer-based reagents [PDF]

, 2014
University of Technology, Sydney. Faculty of Science.Research into latent fingermark detection and visualisation has taken many paths over the years as researchers and practitioners explore numerous methods to improve existing reagents.
Wood, MA
core  

Backbone modified TBA analogues endowed with antiproliferative activity [PDF]

, 2017
Background: Thrombin binding aptamer (TBA) is endowed with antiproliferative properties but its potential development is counteracted by concomitant anticoagulant activity. Methods: Five oligonucleotides (ODNs) based on TBA sequence (GGTTGGTGTGGTTGG) and
AMATO, TERESA, BUCCI, MARIAROSARIA, ESPOSITO, VERONICA, GALEONE, ALDO, RUSSO, ANNAPINA, RUSSO, GIULIA, VARRA, MICHELA, VELLECCO, VALENTINA, VIRGILIO, ANTONELLA   +8 more
core   +1 more source

Selection platforms for directed evolution in synthetic biology [PDF]

, 2016
Life on Earth is incredibly diverse. Yet, underneath that diversity, there are a number of constants and highly conserved processes: all life is based on DNA and RNA; the genetic code is universal; biology is limited to a small subset of potential ...
Amstutz, Attwater, Badran, Baret, Bartel, Baum, Becker, Becker, Bertschinger, Blind, Bock, Breaker, Brudno, Budisa, Cameron, Ceroni, Chin, Chou, Dalby, Damborsky, Daugherty, Delespaul, Deplazes, Derda, Derda, Diamante, Diehl, Doi, Dymond, Eigen, Ellefson, Ellington, Eszter Csibra, Fallah-Araghi, Feng, Fernandez-Gacio, Fischlechner, Gai, Gaj, Ghadessy, Griffiths, Hammerling, Hanes, He, Hoesl, Horiya, Huang, Huebner, Huse, Irving, Isticato, Jestin, Jovicevic, Kaltenbach, Keefe, Kintses, Krumpe, Lane, Larsen, Lee, Leticia Torres, Lipovsek, Liu, Liu, Lundin, Maass, Makowski, Mandell, Marliere, Matochko, Matsuura, Murphy, Odegrip, Packer, Paegel, Pande, Pedro A.G. Tizei, Penchovsky, Pinheiro, Purnick, Quinn, Reiersen, Robertson, Rodi, Rosenbaum, Rovner, Russ, Santoro, Schaerli, Schmidt, Schmidt, Sczepanski, Seelig, Seelig, Sergeeva, Sharma, Shen, Siegel, Sirk, Skirgaila, Smith, Stein, Strauss, Tawfik, Taylor, Taylor, Temme, Temme, Theberge, Tuerk, Uyeda, van Bloois, Vant-Hull, Vitor B. Pinheiro, Wang, Way, Williams, Wochner, Xia, Young, Yu, Yuan, Zhao, Zhou, Zinchenko   +124 more
core   +2 more sources