Results 1 to 10 of about 7,267,221 (342)

Sex-dependent effects of food-restriction on cocaine self-administration and cocaine-seeking in rats [PDF]

Frontiers in Behavioral Neuroscience
IntroductionMisuse of drugs and natural rewards, such as food, share common neural pathways and comparably influence behavioral consequences. Food-restriction enhances drug-taking and drug-seeking behaviors in animals, but the effect of food-restriction ...
Alixandria T. Mascarin, Ava M. Mac, Srinivasu Kallakuri, Mark K. Greenwald, Mark K. Greenwald, Shane A. Perrine   +5 more
doaj   +4 more sources

Cocaine self-administration attenuates brain glucose metabolism and functional connectivity in rats. [PDF]

PLoS One
Rowan C, Hanna C, Sajjad M, Yao R, Sharafsha A, Lewandrowski KU, Blum K, Pinhasov A, Thanos PK.   +8 more
europepmc   +2 more sources

Critical analysis of the achievements of the global millennium development goals and new approaches to sustainable development management [PDF]

E3S Web of Conferences, 2020
This article provides a critical analysis of the achievements of human development towards sustainable development in the 17th Global Goals and reveals new approaches to the management of this process.
Lelechenko Anzhela, Lebedinska Olga, Somin Sergii, Dynnyk Iryna   +3 more
doaj   +1 more source

Practical aspects of the use of antisipative management in the process of ensuring the economic security of an enterprise

Business: Theory and Practice, 2021
Operating in an unstable market economy environment, enterprises can achieve success in business, provided that a system of economic security is created, focused on predicting possible changes in the internal and external environment using measures.
Andriy Shtangret, Elzara Topalova, Oleg Polovcev, Olena Chornenka, Andriy Musiyovskyi   +4 more
doaj   +1 more source

Dynamic Changes of Arc Expression in Dorsal Striatum of Mice After Self-Administration of Sucrose

Frontiers in Cellular Neuroscience, 2021
Region-specific plasticity in the striatal circuit plays an important role in the development and long-term maintenance of skills and sequential movement procedures. Studies investigating the molecular substrates that contribute to the plasticity changes
Xue Li, Jing-Wang Zhao, Qian Ding, Cheng Wu, Wan-Qi Li, Yan-Chen Guo, Di Wang, Guang-Qing Xu, Ti-Fei Yuan, Ti-Fei Yuan, Ti-Fei Yuan, Wan-Kun Gong, Yue Lan, Yue Lan   +13 more
doaj   +1 more source

Evaluation of the implementation of the circular economy in EU countries in the context of sustainable development

Business: Theory and Practice, 2020
The circular economy is interpreted as a stable economic system, which aims at eliminating the consequences and costs, as well as providing a constant cycle of necessary resources. That is why it is so important to conduct its assessment today.
Myroslav Kryshtanovych, Viktoriia Filippova, Maryna Huba, Olga Kartashova, Oleksandr Molnar   +4 more
doaj   +1 more source

Striatal miR-183-5p inhibits methamphetamine-induced locomotion by regulating glucocorticoid receptor signaling

Frontiers in Pharmacology, 2022
MicroRNA (miRNA)-mediated striatal gene regulation may play an important role in methamphetamine (METH) addiction. This study aimed to identify changes in novel miRNAs and their target genes during METH self-administration and investigate their roles in ...
Sang-Hoon Song, Won-Jun Jang, Eun Young Jang, Oc-Hee Kim, Haesoo Kim, Taekwon Son, Dong-Young Choi, Sooyeun Lee, Chul-Ho Jeong   +8 more
doaj   +1 more source

Fentanyl vapor self-administration model in mice to study opioid addiction

Science Advances, 2020
Fentanyl vapor self-administration in mice provides a novel and noninvasive model to study opioid addiction. Intravenous drug self-administration is considered the “gold standard” model to investigate the neurobiology of drug addiction in rodents ...
Khaled Moussawi, Khaled Moussawi, M. M. Ortiz, Stephanie C. Gantz, Stephanie C. Gantz, B. Tunstall, R. Marchette, A. Bonci, G. Koob, L. Vendruscolo   +9 more
semanticscholar   +1 more source

Early Life Stress Promotes Heroin Seeking But Does Not Alter the Excitability of Insular Pyramidal Cells Targeting the Nucleus Accumbens

Frontiers in Behavioral Neuroscience, 2021
A number of retrospective studies have demonstrated adverse childhood experiences are associated with increased vulnerability to substance use disorders, including opioid use disorders (OUDs).
Jonna M. Leyrer-Jackson, Paula F. Overby, Erin K. Nagy, M. Foster Olive   +3 more
doaj   +1 more source

Cannabidiol inhibits sucrose self‐administration by CB1 and CB2 receptor mechanisms in rodents

Addiction Biology, 2020
A growing number of studies suggest therapeutic applications of cannabidiol (CBD), a recently U.S. Food and Drug Administration (FDA)–approved medication for epilepsy, in treatment of many other neuropsychological disorders.
Guo-hua Bi, E. Galaj, Yi He, Z. Xi
semanticscholar   +1 more source