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Finance, Administration, and Operations newsletter, July 2026

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Nicotine self-administration in rats

Psychopharmacology, 1995
Considering the importance of self-administration models in determining mechanisms of drug maintained behavior, we attempted to replicate the findings of nicotine self-administration by Corrigall and Coen. Male, Sprague-Dawley rats, trained on food reinforcement, acquired relatively high and stable rates of self-administration of IV nicotine bitartrate
Eric C. Donny, A R Caggiula
exaly   +3 more sources

Review of self-administration

Drug and Alcohol Dependence, 1985
The reinforcing properties of drugs can be evaluated pre-clinically using self-administration procedures in laboratory animals. This paper reviews self-administration studies of the four opioid agonist/antagonist analgesics pentazocine, butorphanol, nalbuphine and buprenorphine, and compares these results to those from studies of morphine and ...
R L, Balster, S E, Lukas
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Self-administration cues as signals: Drug self-administration and tolerance.

Journal of Experimental Psychology: Animal Behavior Processes, 2001
There is evidence that drug-associated exteroceptive cues elicit compensatory conditional responses (CCRs) that contribute to tolerance. The authors evaluated whether interoceptive, self-administration cues (SACs) similarly contribute to tolerance. In Experiments 1 and 2, the ataxic effect of ethanol was measured in rats that self-administered (SA ...
L, Weise-Kelly, S, Siegel
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Pharmacology of drug self-administration

Alcohol, 1990
Limited access to drugs provides a reliable model for their acute-reinforcing effects and a means by which to explore neuropharmacological mechanisms involved in these effects. In limited access situations intravenous self-administration rates of opiates and psychomotor stimulants is inversely related to dose, and competitive antagonists at low doses ...
G F, Koob, F, Weiss
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Methamphetamine self-administration by humans

Psychopharmacology, 2001
Methamphetamine abuse has become increasingly problematic. Yet, the reinforcing effects of methamphetamine in humans have not been systematically evaluated.To characterize methamphetamine's reinforcing effects in human research participants under controlled laboratory conditions.Eight healthy research volunteers (one female, seven males) completed this
C L, Hart, A S, Ward, M, Haney, R W, Foltin, M W, Fischman   +4 more
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Self-Administration of Morphine in the Cat

International Journal of the Addictions, 1980
Three experiments investigated morphine dependence in the cat. Psychological dependence was measured by self-administration and physiological dependence by induction of withdrawal signs. The data indicate that cats self-administer significantly more morphine than saline. The pattern of morphine self-administrations in cats resembles that which they and
M M, Kilbey, E H, Ellinwood
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Self-administration of medicines

Nursing Standard, 1991
In the fourth of this six-part series on nurse prescribing, Susan Davis assesses the advantages and disadvantages of patient self-administration of medicines in hospital. The former, she asserts, considerably outweigh the latter; a controlled self-administration programme can hasten a patient's progress towards full independence and ease the often ...
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