Adolescent D-amphetamine treatment in a rodent model of ADHD: pro-cognitive effects during adolescence and cocaine abuse risk during adulthood [PDF]
, 2015 Attention-deficit/hyperactivity disorder (ADHD) is comorbid with cocaine abuse. Whereas initiating ADHD medication in childhood does not alter later cocaine abuse risk, initiating medication during adolescence may increase risk.
Baskin, Britahny M. +5 more
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Generation Z in Search of Leadership - Model of Intergenerational Leadership for Creating Commitment (MILCC) [PDF]
Cross-Cultural Management JournalGeneration Z is integrating into the fast-changing work world. The effects of its entry are rapid employee turnover, perceptions of no commitment to organizations, and difficulty in understanding employee needs. This article presents a model for creating
Tidhar LEV
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Frontiers in Psychiatry, 2020 Synthetic cathinones are designer psychostimulants that are derivatives of the natural alkaloid cathinone, and produce effects similar to more traditional illicit stimulants such as cocaine and methamphetamine.
Erin K. Nagy +2 more
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Hypocretin-1 receptors regulate the reinforcing and reward-enhancing effects of cocaine: pharmacological and behavioral genetics evidence. [PDF]
, 2012 Considerable evidence suggests that transmission at hypocretin-1 (orexin-1) receptors (Hcrt-R1) plays an important role in the reinstatement of extinguished cocaine-seeking behaviors in rodents.
Fowler, Christie D +3 more
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An update on CRF mechanisms underlying alcohol use disorders and dependence.
Frontiers in Endocrinology, 2016 Alcohol is the most commonly used and abused substance worldwide. The emergence of alcohol use disorders, and alcohol dependence in particular, is accompanied by functional changes in brain reward and stress systems, which contribute to escalated alcohol
Isabel Marian Hartmann Quadros +3 more
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Glutamatergic Plasticity in Medial Prefrontal Cortex and Ventral Tegmental Area Following Extended-Access Cocaine Self-Administration [PDF]
, 2011 Glutamate signaling in prefrontal cortex and ventral tegmental area plays an important role in the molecular and behavioral plasticity associated with addiction to drugs of abuse.
Ghasemzadeh, Behnam +5 more
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Frontiers in Behavioral Neuroscience, 2014 Tree shrews represent a suitable animal model to study the pathogenesis of human diseases as they are phylogenetically close to primates and have a well-developed central nervous system that possesses many homologies with primates.
Fang eShen +3 more
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Frontiers in Pharmacology, 2012 Maternal smoking during pregnancy is associated with increased substance abuse in offspring. Preclinical research shows that in utero exposure to nicotine, the primary psychoactive compound in tobacco smoke, influences the neurodevelopment of reward ...
Steven Brown Harrod +2 more
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Intravenous self administration of mercury [PDF]
QJM, 2008 A 24-year-old man attempted suicide by intravenous injection of elemental mercury. The exact quantity of injected elemental mercury was unknown. Five days later, the patient presented with painful erythema involving the anterior part of both forearms. On admission, laboratory findings disclosed the following: haemoglobin: 14.5 mmol/l, white blood cell ...
I, Marie +5 more
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The reinforcing properties of ethanol are quantitatively enhanced in adulthood by peri-adolescent ethanol, but not saccharin, consumption in female alcohol-preferring (P) rats [PDF]
, 2015 Alcohol drinking during adolescence is associated in adulthood with heavier alcohol drinking and an increased rate of alcohol dependence. Past research in our laboratory has indicated that peri-adolescent ethanol consumption can enhance the acquisition ...
Bell, Richard L. +7 more
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