Results 31 to 40 of about 956,255 (296)

Methylphenidate treatment beyond adolescence maintains increased cocaine self-administration in the spontaneously hypertensive rat model of attention deficit/hyperactivity disorder [PDF]

open access: yes, 2015
Past research with the spontaneously hypertensive rat (SHR) model of attention deficit/hyperactivity disorder showed that adolescent methylphenidate treatment enhanced cocaine abuse risk in SHR during adulthood.
Baskin, Britahny M.   +2 more
core   +1 more source

Is it stress? The role of stress related systems in chronic food restriction-induced augmentation of heroin seeking in the rat

open access: yesFrontiers in Neuroscience, 2013
Drug addiction is a chronic disease characterized by recurring episodes of abstinence and relapse. The precise mechanisms underlying this pattern are yet to be elucidated, but stress is thought to be a major factor in relapse.
Firas eSedki   +5 more
doaj   +1 more source

Case report: Self-administration of alpha-1 antitrypsin therapy: a report of two cases

open access: yesFrontiers in Pharmacology, 2023
Intravenous augmentation therapy with human alpha-1 proteinase inhibitor for the management of respiratory disease is recommended for people with alpha-1 antitrypsin deficiency (AATD) who are nonsmokers or former smokers.
Ana M. Escribano Dueñas   +3 more
doaj   +1 more source

Nicotine self‐administration in rats [PDF]

open access: yesBritish Journal of Pharmacology, 1984
Female Wistar rats were allowed to self‐administer nicotine solutions through indwelling jugular vein cannulae for 23 h per day for periods from three to five weeks. Two response levers were available to the rats; responding on one lever, designated the active lever, produced an immediate infusion of nicotine solution or saline.
B M, Cox, A, Goldstein, W T, Nelson
openaire   +2 more sources

Recent updates on incubation of drug craving: a mini-review [PDF]

open access: yes, 2015
Cue-induced drug craving progressively increases after prolonged withdrawal from drug self-administration in laboratory animals, a behavioral phenomenon termed 'incubation of drug craving.' Studies over the years have revealed several important neural ...
Abdolahi   +39 more
core   +1 more source

Compliance of the regulation of supervision over local government in the Polish Constitution and in legal acts

open access: yesКонституційно-правові академічні студії
The aim of the article will be to analyze the regulation of supervision over local government in the Polish Constitution and in the legal system regulating the supervision of local government.
Kazimierz Bandarzewski
doaj   +1 more source

Disaster Risk Reduction for Sustainable Development Goals [PDF]

open access: yesEuropean Project Management Journal, 2017
Our civilization is witnessing the devastating power of natural disasters all over the world. Unfortunately, it is evident that the number and intensity of disasters increased over time. Consequently, grate number of victims and material damage force the
Nataša Petrović   +2 more
doaj  

ENDOCANNABINOID 2-ARACHIDONOYLGLYCEROL SELF-ADMINISTRATION BY SPRAGUE-DAWLEY RATS AND STIMULATION OF IN VIVO DOPAMINE TRANSMISSION IN THE NUCLEUS ACCUMBENS SHELL

open access: yesFrontiers in Psychiatry, 2014
2-Arachidonoylglycerol (2-AG) is the most potent endogenous ligand of brain cannabinoid CB1 receptors and is synthesized on demand from 2-arachidonate-containing phosphoinositides by the action of diacyglycerol lipase in response to increased ...
Maria Antonietta eDe Luca   +9 more
doaj   +1 more source

Impact of tobacco smoke constituents on nicotine-seeking behavior in adolescent and adult male rats

open access: yesFrontiers in Psychiatry, 2023
IntroductionGiven the rapid increase in teen vaping over recent years it is critical to understand mechanisms underlying addiction and relapse to tobacco use at this age.
Candice A. Gellner   +3 more
doaj   +1 more source

Serotonin-3 Receptors in the Posterior Ventral Tegmental Area Regulate Ethanol Self-Administration of Alcohol-Preferring (P) Rats [PDF]

open access: yes, 2010
Several studies indicated the involvement of serotonin-3 (5-HT 3 ) receptors in regulating alcohol- drinking behavior. The objective of this study was to determine the involvement of 5-HT 3 receptors within the ventral tegmental area (VTA) in ...
Beardsley   +52 more
core   +1 more source

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