Results 31 to 40 of about 7,267,221 (342)

Varied behavioral responses induced by morphine in the tree shrew: a possible model for human opiate addiction

Frontiers in Behavioral Neuroscience, 2014
Tree shrews represent a suitable animal model to study the pathogenesis of human diseases as they are phylogenetically close to primates and have a well-developed central nervous system that possesses many homologies with primates.
Fang eShen, Ying eDuan, Shu bo eJin, Nan eSui   +3 more
doaj   +1 more source

Serotonin-3 Receptors in the Posterior Ventral Tegmental Area Regulate Ethanol Self-Administration of Alcohol-Preferring (P) Rats [PDF]

, 2010
Several studies indicated the involvement of serotonin-3 (5-HT 3 ) receptors in regulating alcohol- drinking behavior. The objective of this study was to determine the involvement of 5-HT 3 receptors within the ventral tegmental area (VTA) in ...
Beardsley, Campbell, Carboni, Ding, Ding, Fadda, Ford, Gatto, Herve, Hodge, Hodge, Hodge, Ikemoto, Ikemoto, Ikemoto, Ikemoto, James M. Murphy, Jamie E. Toalston, Katner, Klein, Knapp, Koob, Liu, Liu, Lovinger, McKinzie, McKinzie, Minabe, Nowak, Nowak, Paxinos, Prisco, Rasmussen, Richard L. Bell, Rodd, Rodd, Rodd, Rodd, Rodd, Rodd, Rodd-Henricks, Rodd-Henricks, Rodd-Henricks, Scott M. Oster, Sung, Svensson, Toalston, Tomkins, Tylene J. Pommer, Van Bockstaele, William J. McBride, Wozniak, Zachary A. Rodd   +52 more
core   +1 more source

Self-administration of injectable contraception: a systematic review and meta-analysis

BMJ Global Health, 2019
Introduction Depot medroxyprogesterone acetate subcutaneous injectable contraception (DMPA-SC) may facilitate self-administration and expand contraceptive access.
C. Kennedy, P. Yeh, M. Gaffield, M. Brady, Manjulaa Narasimhan   +4 more
semanticscholar   +1 more source

Offspring of prenatal IV nicotine exposure exhibit increased sensitivity to the reinforcing effects of methamphetamine

Frontiers in Pharmacology, 2012
Maternal smoking during pregnancy is associated with increased substance abuse in offspring. Preclinical research shows that in utero exposure to nicotine, the primary psychoactive compound in tobacco smoke, influences the neurodevelopment of reward ...
Steven Brown Harrod, Ryan T. Lacy, Amanda J. Morgan   +2 more
doaj   +1 more source

The reinforcing properties of ethanol are quantitatively enhanced in adulthood by peri-adolescent ethanol, but not saccharin, consumption in female alcohol-preferring (P) rats [PDF]

, 2015
Alcohol drinking during adolescence is associated in adulthood with heavier alcohol drinking and an increased rate of alcohol dependence. Past research in our laboratory has indicated that peri-adolescent ethanol consumption can enhance the acquisition ...
Bell, Richard L., Deehan Jr., Gerald A., Engleman, Eric A., Hauser, Sheketha R., McBride, William J., Murphy, James M., Rodd, Zachary A., Toalston, Jamie E.   +7 more
core   +1 more source

Transcranial Magnetic Stimulation of Medial Prefrontal and Cingulate Cortices Reduces Cocaine Self-Administration: A Pilot Study

Frontiers in Psychiatry, 2018
Background Previous studies have shown that repetitive transcranial magnetic stimulation (rTMS) to the dorsolateral prefrontal cortex may serve as a potential treatment for cocaine use disorder (CUD), which remains a public health problem that is ...
D. Martínez, N. Urban, A. Grassetti, D. Chang, Mei-Chen Hu, A. Zangen, F. Levin, R. Foltin, E. Nunes   +8 more
semanticscholar   +1 more source

Is it stress? The role of stress related systems in chronic food restriction-induced augmentation of heroin seeking in the rat

Frontiers in Neuroscience, 2013
Drug addiction is a chronic disease characterized by recurring episodes of abstinence and relapse. The precise mechanisms underlying this pattern are yet to be elucidated, but stress is thought to be a major factor in relapse.
Firas eSedki, Zarish eAbbas, Staci eAngelis, Jeffrey eMartin, Tracey eD'Cunha, Uri eShalev   +5 more
doaj   +1 more source

Recent updates on incubation of drug craving: a mini-review [PDF]

, 2015
Cue-induced drug craving progressively increases after prolonged withdrawal from drug self-administration in laboratory animals, a behavioral phenomenon termed 'incubation of drug craving.' Studies over the years have revealed several important neural ...
Abdolahi, Bedi, Bienkowski, Chauvet, Chauvet, Conrad, Counotte, Fanous, Gawin, Grimm, Grimm, Guillem, Halbout, Hollander, Koya, Krasnova, Lee, Li, Li, Li, Loweth, Lu, Lu, Lu, Ma, Marchant, Neisewander, Pickens, Purgianto, Shalev, Shepard, Solinas, Sorge, Theberge, Thiel, Thiel, Tran-Nguyen, Uejima, Wang, Xi   +39 more
core   +1 more source

Disaster Risk Reduction for Sustainable Development Goals [PDF]

European Project Management Journal, 2017
Our civilization is witnessing the devastating power of natural disasters all over the world. Unfortunately, it is evident that the number and intensity of disasters increased over time. Consequently, grate number of victims and material damage force the
Nataša Petrović, Ivan Bošnjak, Sandra Nedeljković   +2 more
doaj  

ENDOCANNABINOID 2-ARACHIDONOYLGLYCEROL SELF-ADMINISTRATION BY SPRAGUE-DAWLEY RATS AND STIMULATION OF IN VIVO DOPAMINE TRANSMISSION IN THE NUCLEUS ACCUMBENS SHELL

Frontiers in Psychiatry, 2014
2-Arachidonoylglycerol (2-AG) is the most potent endogenous ligand of brain cannabinoid CB1 receptors and is synthesized on demand from 2-arachidonate-containing phosphoinositides by the action of diacyglycerol lipase in response to increased ...
Maria Antonietta eDe Luca, Maria Antonietta eDe Luca, Valentina eValentini, Valentina eValentini, Zisis eBimpisidis, Fabio eCacciapaglia, Pierluigi eCaboni, Gaetano eDi Chiara, Gaetano eDi Chiara, Gaetano eDi Chiara   +9 more
doaj   +1 more source