Results 41 to 50 of about 7,366,469 (392)

Reinforcing Effects of the Synthetic Cathinone α-Pyrrolidinopropiophenone (α-PPP) in a Repeated Extended Access Binge Paradigm

open access: yesFrontiers in Psychiatry, 2020
Synthetic cathinones are designer psychostimulants that are derivatives of the natural alkaloid cathinone, and produce effects similar to more traditional illicit stimulants such as cocaine and methamphetamine.
Erin K. Nagy   +2 more
doaj   +1 more source

Transcranial Magnetic Stimulation of Medial Prefrontal and Cingulate Cortices Reduces Cocaine Self-Administration: A Pilot Study

open access: yesFrontiers in Psychiatry, 2018
Background Previous studies have shown that repetitive transcranial magnetic stimulation (rTMS) to the dorsolateral prefrontal cortex may serve as a potential treatment for cocaine use disorder (CUD), which remains a public health problem that is ...
D. Martínez   +8 more
semanticscholar   +1 more source

Involvement of the Cuneate Nucleus in the Acupuncture Inhibition of Drug-Seeking Behaviors

open access: yesFrontiers in Neuroscience, 2019
Our previous studies have shown that acupuncture suppresses addictive behaviors induced by drugs of abuse, including cocaine, morphine and ethanol, by modulating GABA neurons in the ventral tegmental area (VTA) and dopamine (DA) release in the nucleus ...
Suchan Chang   +10 more
doaj   +1 more source

Enhanced self-administration of the CB1 receptor agonist WIN55,212-2 in olfactory bulbectomized rats: evaluation of possible serotonergic and dopaminergic underlying mechanisms [PDF]

open access: yes, 2014
Depression has been associated with drug consumption, including heavy or problematic cannabis use. According to an animal model of depression and substance use disorder comorbidity, we combined the olfactory bulbectomy (OBX) model of depression with ...
Amchova P   +11 more
core   +1 more source

Region-Specific Reductions in Morphometric Properties and Synaptic Colocalization of Astrocytes Following Cocaine Self-Administration and Extinction

open access: yesFrontiers in Cellular Neuroscience, 2018
While much is known about the effects of cocaine use on the cellular structure and function of neurons and synapses within the brain’s reward circuitry, relatively little is known about the effects of cocaine on astrocytes.
A. Testen   +3 more
semanticscholar   +1 more source

Effects of morphine self-administration on brain glucose metabolism in rats [PDF]

open access: yes, 2006
of: AMI Annual Conference 2006, March 25-29Chronic exposure to opiates has been shown to influence neural activity in brain regions related to the rewarding process. It also induces neuroadaptations which lead to addiction.
Ambrosio, E.   +9 more
core   +9 more sources

Glutamatergic Plasticity in Medial Prefrontal Cortex and Ventral Tegmental Area Following Extended-Access Cocaine Self-Administration [PDF]

open access: yes, 2011
Glutamate signaling in prefrontal cortex and ventral tegmental area plays an important role in the molecular and behavioral plasticity associated with addiction to drugs of abuse.
Ghasemzadeh, Behnam   +5 more
core   +2 more sources

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis   +9 more
wiley   +1 more source

The Effects of Excitatory and Inhibitory Social Cues on Cocaine-Seeking Behavior

open access: yesFrontiers in Behavioral Neuroscience, 2016
Social partners influence the likelihood of using drugs, developing a substance use disorder, and relapse to drug use after a period of abstinence. Preclinical studies report that social cues influence the acquisition of cocaine use, the escalation of ...
Mark Andrew Smith   +2 more
doaj   +1 more source

Exercise decreases speedball self-administration [PDF]

open access: yesLife Sciences, 2014
Epidemiological studies report that individuals who exercise are less likely to abuse drugs. Preclinical studies report that exercise, in the form of treadmill or wheel running, reliably decreases the self-administration of psychomotor stimulants and opioids.
Ryan T, Lacy   +4 more
openaire   +2 more sources

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