Results 71 to 80 of about 45,149 (166)

The interplay between the hippocampus and the amygdala in regulating aberrant hippocampal neurogenesis during protracted abstinence from alcohol dependence

Frontiers in Psychiatry, 2013
The development of alcohol dependence involves elevated anxiety, low mood, and increased sensitivity to stress, collectively labeled negative affect. Particularly interesting is the recent accumulating evidence that sensitized extrahypothalamic stress ...
Chitra D Mandyam
doaj   +1 more source

Home self-administration of omalizumab

Journal of Dermatological Treatment, 2017
Dear Editor,Chronic spontaneous urticaria is an itching skin disease characterized by wheals and/or angioedema persisting for more than 6 weeks.
Ghazanfar, Misbah Noshela, Thomsen, Simon Francis   +1 more
openaire   +3 more sources

Nicotine Increases Alcohol Intake in Adolescent Male Rats [PDF]

, 2017
Background: Use of alcohol and tobacco, the two most concurrently abused drugs, typically first occurs during adolescence. Yet, there have been no systematic analyses of ethanol (EtOH) and nicotine (Nic) interactions during adolescence.
Armando Lárraga, Frances M. Leslie, James D. Belluzzi   +2 more
core   +1 more source

Detrimental Effects of a Retrieval-Extinction Procedure on Nicotine Seeking, but Not Cocaine Seeking

Frontiers in Behavioral Neuroscience, 2019
Retrieval-extinction memory reactivation procedures have been used to prevent the return of learned fear and drug seeking in preclinical models. These procedures first reactivate the original memory with a brief cue exposure (i.e., retrieval) session ...
Roeland F. Struik, Taco J. De Vries, Jamie Peters, Jamie Peters   +3 more
doaj   +1 more source

Histamine H3 receptor: A novel therapeutic target in alcohol dependence?

Frontiers in Systems Neuroscience, 2012
The brain histaminergic system is one of the diffuse modulatory neurotransmitter systems which regulate neuronal activity in many brain areas. Studies on both rats and mice indicate that histamine H3 receptor antagonists decrease alcohol drinking in ...
Pertti ePanula, Saara eNuutinen, Jenni eVanhanen, Tiia eMäki   +3 more
doaj   +1 more source

DNMT3a in the hippocampal CA1 is crucial in the acquisition of morphine self‐administration in rats [PDF]

, 2019
Drug‐reinforced excessive operant responding is one fundamental feature of long-lasting addiction‐like behaviors and relapse in animals. However, the transcriptional regulatory mechanisms responsible for the persistent drug‐specific (not natural rewards)
Duan, Ying, Jiang, Feng-Ze, Jin, Su-Bo, Li, Ming, Liang, Jing, Shen, Fang, Sui, Nan, Zhang, Jian-Jun, Zheng, Wei   +8 more
core   +1 more source

Disruption of long-term alcohol-related memory reconsolidation: Role of β-adrenoceptors and NMDA receptors

Frontiers in Behavioral Neuroscience, 2010
Disrupting reconsolidation of drug-related memories may be effective in reducing the incidence of relapse. In the current study we examine whether alcohol- related memories are prone to disruption by the β -adrenergicreceptor antagonist propranolol (
Jelte A Wouda, Leontien Diergaarde, Danai Riga, Yvar Van Mourik, Anton N M Schoffelmeer, Taco J De Vries   +5 more
doaj   +1 more source

Varenicline decreases nicotine but not alcohol self-administration in genetically selected Marchigian Sardinian alcohol-preferring (msP) rats [PDF]

, 2015
Background: Alcohol and nicotine are largely co-abused. Here, we investigated whether concurrent exposure to both addictive drugs influences each other's consumption and whether varenicline attenuates alcohol consumption in the presence of nicotine ...
Ciccocioppo, Roberto, Cippitelli, Andrea, Scuppa, Giulia, Toll, Lawrence, Ubaldi, Massimo   +4 more
core   +1 more source

Astrocyte Ca2+ in the dorsal striatum suppresses neuronal activity to oppose cue-induced reinstatement of cocaine seeking

Frontiers in Cellular Neuroscience
Recent literature supports a prominent role for astrocytes in regulation of drug-seeking behaviors. The dorsal striatum, specifically, is known to play a role in reward processing with neuronal activity that can be influenced by astrocyte Ca2+.
Navid S. Tavakoli, Samantha G. Malone, Tanner L. Anderson, Ryson E. Neeley, Artin Asadipooya, Michael T. Bardo, Pavel I. Ortinski   +6 more
doaj   +1 more source

Levo-Tetrahydropalmatine Attenuates Cocaine Self-Administration under a Progressive-Ratio Schedule and Cocaine Discrimination in Rats [PDF]

, 2010
Levo-tetrahydropalmatine (l-THP) is an alkaloid found in many traditional Chinese herbal preparations and has a unique pharmacological profile that includes dopamine receptor antagonism.
Baker, David A., Becker, Amanda, Li, Shi-Jiang, Mantsch, John R., Peters, Corey, Valentine, Abbey, Vranjkovic, Oliver, Wisniewski, Samantha, Yang, Zheng   +8 more
core   +2 more sources