Results 91 to 100 of about 28,679 (139)

Alphaviral backbone of self-amplifying RNA enhances protein expression and immunogenicity against SARS-CoV-2 antigen. [PDF]

Mol Ther
Casmil IC, Bathula NV, Huang C, Wayne CJ, Cairns ES, Friesen JJ, Soriano SK, Liao S, Ho CH, Kong KYS, Blakney AK.   +10 more
europepmc   +1 more source

A self-amplifying RNA RSV prefusion-F vaccine elicits potent immunity in pre-exposed and naïve non-human primates. [PDF]

Nat Commun
Vijayan A, Vogels R, Groppo R, Jin Y, Khan S, Van Kampen M, Jorritsma S, Boedhoe S, Baert M, van Diepen H, Kuipers H, Serroyen J, Del Valle JR, Broman A, Nguyen L, Ray S, Jarai B, Arora J, Lifton M, Mildenberg B, Morton G, Santra S, Grossman TR, Schuitemaker H, Custers J, Zahn R.   +25 more
europepmc   +1 more source

A self-amplifying RNA vaccine prevents enterovirus D68 infection and disease in preclinical models. [PDF]

Sci Transl Med
Warner NL, Archer J, Park S, Singh G, McFadden KM, Kimura T, Nicholes K, Simpson A, Kaelber JT, Hawman DW, Feldmann H, Khandhar AP, Berglund P, Vogt MR, Erasmus JH.   +14 more
europepmc   +1 more source

Complete substitution with modified nucleotides in self-amplifying RNA suppresses the interferon response and increases potency. [PDF]

Nat Biotechnol
McGee JE, Kirsch JR, Kenney D, Cerbo F, Chavez EC, Shih TY, Douam F, Wong WW, Grinstaff MW.   +8 more
europepmc   +1 more source

A Lipid Nanoparticle-Formulated Self-Amplifying RNA Rift Valley Fever Vaccine Induces a Robust Humoral Immune Response in Mice. [PDF]

Vaccines (Basel)
Kitandwe PK, Rogers P, Hu K, Nayebare O, Blakney AK, McKay PF, Kaleebu P, Shattock RJ.   +7 more
europepmc   +1 more source

Biophysical characterisation of the structure of a SARS-CoV-2 self-amplifying - RNA (saRNA) vaccine

, 2022
Myatt DP, Wharram L, Graham C, Liddell J, Branton H, Pizzey C, Cowieson N, Rambo R, Shattock RJ.   +8 more
europepmc   +1 more source

Semliki Forest Virus (SFV) Self-Amplifying RNA Delivered to J774A.1 Macrophage Lineage by Its Association with a Purified Recombinant SFV Capsid Protein. [PDF]

Int J Mol Sci
Gomes RP, Barbosa FF, Toledo MAS, Jorge SAC, Astray RM.   +4 more
europepmc   +1 more source

Optimizing immunogenicity and product presentation of a SARS-CoV-2 subunit vaccine composition: effects of delivery route, heterologous regimens with self-amplifying RNA vaccines, and lyophilization. [PDF]

Front Immunol
Lykins WR, Pollet J, White JA, Keegan B, Versteeg L, Strych U, Chen WH, Mohamath R, Ramer-Denisoff G, Reed S, Renshaw C, Beaver S, Gerhardt A, Voigt EA, Tomai MA, Sitrin R, Choy RKM, Cassels FJ, Hotez PJ, Bottazzi ME, Fox CB.   +20 more
europepmc   +1 more source

Charge neutralized poly(β-amino ester) polyplex nanoparticles for delivery of self-amplifying RNA. [PDF]

Nanoscale Adv
Dastgerdi NK, Gumus N, Bayraktutan H, Jackson D, Polra K, McKay PF, Atyabi F, Dinarvand R, Shattock RJ, Martinez-Pomares L, Gurnani P, Alexander C.   +11 more
europepmc   +1 more source

Safety and immunogenicity of VLPCOV-02, a SARS-CoV-2 self-amplifying RNA vaccine with a modified base, 5-methylcytosine. [PDF]

iScience
Aboshi M, Matsuda K, Kawakami D, Kono K, Kazami Y, Sekida T, Komori M, Morey AL, Suga S, Smith JF, Fukuhara T, Iwatani Y, Yamamoto T, Sato N, Akahata W.   +14 more
europepmc   +1 more source