Dynamic responsiveness of self‐assembling peptide‐based nano‐drug systems
Interdisciplinary Medicine, 2023 Dynamic‐responsive self‐assembly is the process of ordered supramolecular structure formation or reversible decomposition from building blocks. This process is driven by non‐covalent interactions based on complex stimulus‐responsive systems comprising ...
Yuhan Wang +6 more
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Self-assembling peptide-enriched electrospun polycaprolactone scaffolds promote the h-osteoblast adhesion and modulate differentiation-associated gene expression [PDF]
, 2004 Electrospun polycaprolactone (PCL) is able to support the adhesion and growth of h-osteoblasts and to delay their degradation rate to a greater extent with respect to other polyesters. The drawbacks linked to its employment in regenerative medicine arise
Brun, Paola +10 more
core +1 more source
Self-assembly of bioactive peptides, peptide conjugates, and peptide-mimetic materials [PDF]
, 2017 Molecular self-assembly is a multi-disciplinary field of research, with potential chemical and biological applications. One of the main driving forces of self-assembly is molecular amphiphilicity, which can drive formation of complex and stable ...
Ahmed +127 more
core +1 more source
Impact of C-Terminal Chemistry on Self-Assembled Morphology of Guanosine Containing Nucleopeptides
Molecules, 2020 Herein, we report the design and characterization of guanosine-containing self-assembling nucleopeptides that form nanosheets and nanofibers. Through spectroscopy and microscopy analysis, we propose that the peptide component of the nucleopeptide drives ...
Katherine Boback +5 more
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Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity. [PDF]
, 2017 Peptide-based supramolecular assemblies are a promising class of nanomaterials with important biomedical applications, specifically in drug delivery and tissue regeneration.
Adler-Abramovich, Lihi +10 more
core +3 more sources
Probing the dynamic nature of self-assembling cyclic peptide-polymer nanotubes in solution and in mammalian cells [PDF]
, 2017 Self-assembling cyclic peptide–polymer nanotubes have emerged as a fascinating supramolecular system, well suited for a diverse range of biomedical applications.
Brendel, Johannes C. +7 more
core +1 more source
Self-assembling peptide scaffolds in the clinic
npj Regenerative Medicine, 2021 Well-defined scaffold hydrogels made of self-assembling peptides have found their way into clinical products. By examining the properties and applications of two self-assembling peptides—EAK16 and RADA16—we highlight the potential for translating ...
Fabrizio Gelain +3 more
doaj +1 more source
Molecular dynamics simulations reveal disruptive self-assembly in dynamic peptide libraries [PDF]
, 2017 There is a significant interest in the use of unmodified self-assembling peptides as building blocks for functional, supramolecular biomaterials. Recently, dynamic peptide libraries (DPLs) have been proposed to select self-assembling materials from ...
Moreira, I. P. +3 more
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Mediators of Inflammation, 2012 Nanostructured, self-assembling peptides hold promise for a variety of regenerative medical applications such as 3D cell culture systems, accelerated wound healing, and nerve repair.
Woo Seok Yang +8 more
doaj +1 more source
Solvent modulation in peptide sub-microfibers obtained by solution blow spinning
Frontiers in Chemistry, 2022 Peptides possess high chemical diversity at the amino acid sequence level, which further translates into versatile functions. Peptides with self-assembling properties can be processed into diverse formats giving rise to bio-based materials. Peptide-based
Ana Margarida Gonçalves Carvalho Dias +10 more
doaj +1 more source