Results 61 to 70 of about 5,171,640 (300)
Self-Assembling Peptide-Based Nanoarchitectonics
, 2019 Self-assembly is omnipresent in nature. While natural self-assembly systems are complicated in structure, the simplification of natural systems while maintaining their inherent functionalities has proven to be a highly promising route towards artificial ...
Yan, Xuehai, Zou, Qianli, Zhao, Luyang
core +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Engineering self-assembling peptide scaffolds for controlled delivery of viral vector serotypes
, 2022 Engineering self-assembling peptide scaffolds for controlled delivery of viral vector ...
Leszek Lisowski (15442586) +6 more
core +1 more source
Biomimetic Remineralization of Carious Lesions by Self-Assembling Peptide [PDF]
, 2017 Self-assembling β-sheet forming peptide P11-4 has shown potential in the treatment and prevention of dental caries by supporting tissue regeneration. It has previously been shown that application of monomeric P11-4 solution to early carious lesions can ...
Hofer, Joëlle +20 more
core +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Cooperative Self-Assembly of Peptide Gelators and Proteins [PDF]
Biomacromolecules, 2013 Abstract Molecular self-assembly provides a versatile route for the production of nanoscale materials for medical and technological applications. Herein, we demonstrate that the cooperative self-assembly of amphiphilic small molecules and proteins can have drastic effects on supramolecular nanostructuring of resulting materials.
Javid, Nadeem +5 more
openaire +4 more sources
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Hydroxyapatite Surfaces Functionalized with a Self-Assembling Peptide: XPS, RAIRS and NEXAFS Study
Nanomaterials, 2020 Hydroxyapatite (HAP) coatings can improve the biocompatibility and bioactivity of titanium alloys, such as Ti6Al4V, commonly used as material for orthopedic prostheses.
Valeria Secchi +9 more
doaj +1 more source
Amyloid Inspired Self-Assembled Peptide Nanofibers [PDF]
Biomacromolecules, 2012 Amyloid peptides are important components in many degenerative diseases as well as in maintaining cellular metabolism. Their unique stable structure provides new insights in developing new materials. Designing bioinspired self-assembling peptides is essential to generate new forms of hierarchical nanostructures.
Cinar G. +7 more
openaire +5 more sources