Results 51 to 60 of about 320,703 (322)

Protein O‐glycosylation in the Bacteroidota phylum

open access: yesFEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns   +2 more
wiley   +1 more source

Creating amphiphilic porosity in two-dimensional covalent organic frameworks via steric-hindrance-mediated precision hydrophilic-hydrophobic microphase separation

open access: yesNature Communications
Creating different pore environments within a covalent organic framework (COF) will lead to useful multicompartment structure and multiple functions, which however has been scarcely achieved.
Shu-Yan Jiang   +7 more
doaj   +1 more source

Graphene Oxide/Ferrocene-Containing Polymer/Gold Nanoparticle Triple Nanocomposite

open access: yesNanomaterials, 2019
A facile strategy to prepare GO-based nanocomposites with both gold nanoparticles (AuNPs) and ferrocene (Fc) moieties was developed. The surface of GO was modified with PFcMAss homopolymer by surface-initiated atom transfer radical polymerization of a ...
Wenhao Qian   +6 more
doaj   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Biocatalytic Self‐Assembly Cascades [PDF]

open access: yesAngewandte Chemie, 2017
AbstractThe properties of supramolecular materials are dictated by both kinetic and thermodynamic aspects, providing opportunities to dynamically regulate morphology and function. Herein, we demonstrate time‐dependent regulation of supramolecular self‐assembly by connected, kinetically competing enzymatic reactions.
Yousef M. Abul-Haija   +6 more
openaire   +3 more sources

Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis

open access: yesAdvanced Biology, EarlyView.
Transmembrane signaling is the hallmark of living cells and is among the highest challenges for the design of synthetic cells. Herein, an artificial receptor based on the chemistry of self‐immolative linkers is used to communicate information across the lipid bilayer, for transmembrane activation of enzymatic activity. Abstract The design of artificial,
Ane Bretschneider Søgaard   +7 more
wiley   +1 more source

OrthoID: profiling dynamic proteomes through time and space using mutually orthogonal chemical tools

open access: yesNature Communications
Identifying proteins at organelle contact sites, such as mitochondria-associated endoplasmic reticulum membranes (MAM), is essential for understanding vital cellular processes, yet challenging due to their dynamic nature.
Ara Lee   +14 more
doaj   +1 more source

Hijacking Self‐Assembly to Establish Intracellular Functional Nanoparticles

open access: yesAdvanced Science, 2022
The targeted transport of nanomedicines is often impeded by various biological events in the body. Viruses can hijack host cells and utilize intracellular transcription and translation biological events to achieve their replication.
Yang Liu   +8 more
doaj   +1 more source

Bayesian model calibration for block copolymer self-assembly: Likelihood-free inference and expected information gain computation via measure transport [PDF]

open access: yesarXiv, 2022
We consider the Bayesian calibration of models describing the phenomenon of block copolymer (BCP) self-assembly using image data produced by microscopy or X-ray scattering techniques. To account for the random long-range disorder in BCP equilibrium structures, we introduce auxiliary variables to represent this aleatory uncertainty.
arxiv  

Self‐assembly of collagen [PDF]

open access: yesJournal of Supramolecular Structure, 1974
AbstractThe structure and self‐assembly of collagen and procollagen molecules are reviewed. The registration peptides of procollagen have specific recognition properties which assure (1) selection of component polypeptide chains and (2) registration of their N‐termini, facilitating orderly folding into a collagen helix.
openaire   +3 more sources

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