Results 61 to 70 of about 1,801,493 (278)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Continuous weak measurement and feedback control of a solid-state charge qubit: physical unravelling of non-Lindblad master equation

, 2006
Conventional quantum trajectory theory developed in quantum optics is largely based on the physical unravelling of Lindbald-type master equation, which constitutes the theoretical basis of continuous quantum measurement and feedback control. In this work,
H. J. Carmichael, Hsi-Sheng Goan, Jinshuang Jin, R. Ruskov, Shi-Kuan Wang, Xin-Qi Li   +5 more
core   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

The Effect of Negative Feedback on Positive Beliefs in Self-Deception

Frontiers in Psychology, 2019
In the present study, we applied the forward-looking paradigm to examine how positive beliefs appear in self-deception and to further reveal the influence of negative feedback on positive beliefs to decrease self-deception.
Juan Liu, Juan Liu, Wenjie Zhang, Wenjie Zhang, Youlong Zhan, Lixin Song, Peipei Guan, Dan Kang, Jie Jian, Jie Jian, Ronghua Cai, Mei Li, Mei Li   +12 more
doaj   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Self-tuning, load-mitigating feedback control of a 3-DOF point absorber

International Marine Energy Journal, 2022
A simple, self-tuning multi-objective controller is demonstrated in simulation for a 3-DOF (surge, heave, pitch) point absorber. In previous work, the proposed control architecture has been shown to be effective in experiments for a variety of device ...
Dominic D Forbush, Giorgio Bacelli, Ryan G Coe   +2 more
doaj   +1 more source

A self optimizing synthetic organic reactor system using real-time in-line NMR spectroscopy [PDF]

, 2015
A configurable platform for synthetic chemistry incorporating an in-line benchtop NMR that is capable of monitoring and controlling organic reactions in real-time is presented.
Cronin, Leroy, Dragone, Vincenza, Porwol, Luzian, Sans Sangorrin, Victor   +3 more
core   +2 more sources

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Contextual Interference Effect in Bandwidth and Self-Control Feedback Conditions on Relative and Absolute Timing Learning

Annals of Applied Sport Science, 2016
This study aims to better understand the effect of practice schedule and feedback providing types. In two separate experiments the contextual interference effect in bandwidth and self-control feedback conditions on relative and absolute timing learning ...
Amir Shams, Seyedeh Mansoreh Naeimi Tajdar   +1 more
doaj  

Non-cooperative Feedback Rate Control Game for Channel State Information in Wireless Networks

, 2011
It has been well recognized that channel state information (CSI) feedback is of great importance for dowlink transmissions of closed-loop wireless networks.
Han, Zhu, Jiao, Bingli, Song, Lingyang, Zhang, Zhongshan   +3 more
core   +1 more source