Results 41 to 50 of about 14,472,907 (287)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Instructional feedback to support self-regulated writing in primary school
Frontiers in Education, 2023 Feedback that enhances self-regulated learning when writing seems to rarely be provided in classrooms to beginner writers, although acting autonomously as a writer is crucial for the pupils’ further literacy development.
Pernille Fiskerstrand, Siv M. Gamlem
doaj +1 more source
Sports Medicine and Health ScienceSelf-modeling (SM) and self-control (SC) feedback can be presented as two solutions for learning improvement. Therefore, the aim of the present study was to investigate the effects of SM and SC feedback on 100-m freestyle performance of professional ...
Masoud Mirmoezzi +10 more
doaj +1 more source
Acta Gymnica, 2019 Background: Although the useful effects of self-controlled feedback on motor skills learning have been proven, a study dealing with the effects of self-controlled and instructor-controlled feedback on learning and intrinsic motivation among novice ...
Reza Goudini +2 more
doaj +1 more source
Optimal Learning and Self-Awareness Versus PDI
Algorithms, 2020 This manuscript will explore and analyze the effects of different paradigms for the control of rigid body motion mechanics. The experimental setup will include deterministic artificial intelligence composed of optimal self-awareness statements together ...
Brendon Smeresky +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
System Science Principle of the Mechanism of Acupuncture and Moxibustion
Yixue yu zhexueHuman body is a complex yet orderly system—an archetypal self-organization entity characterized by functions such as self-regulation, self-control, and self-repair, all of which rely heavily on the operation of negative feedback mechanisms.
Biwei CHEN +3 more
doaj +1 more source