Results 91 to 100 of about 7,385,969 (371)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Self-Determination Right of Indigenous Peoples

open access: yesМосковский журнал международного права, 2010
Self-Determination Right is still an object of dispute among international jurists. It often becomes a stumbling block and leads to inter-ethnic conflicts.
R. S. Garipov
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

PROFESSIONAL SELF-DETERMINATION AS A SOCIAL AND CULURAL PROCESS

open access: yesВестник Кемеровского государственного университета, 2014
Professional self-determination is an important factor of socialization and self-identity not only in a specific professional field. The paper analyzes the essence of professional self-determination based on an integrated multidisciplinary approach ...
I. A. Levitskaya
doaj  

Psychological potential of personal self-realization

open access: yesSocial Welfare: Interdisciplinary Approach, 2016
The article reveals the psychological foundations of the self-realization phenomenon. It shows that personal self-realization as a self-determined phenomenon is determined by a complex of interconnected personal indicators, including the value of self ...
Sergiy Maksimenko, Liudmyla Serdiuk
doaj   +1 more source

ESOPs & CO-OPs: Worker Capitalism & Worker Democracy [PDF]

open access: yes, 1985
[Excerpt] The broad purpose of the labor movement has always been to further the economic self-determination of workers, to maximize working people\u27s control over their economic destiny. Self-determination is the goal, but what are the means?
Ellerman, David P.
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Characteristics of Self-efficacy in the Space of an Individual’s Self-determination

open access: yesПроблеми сучасної психології, 2019
The results of the theoretical and experimental research on selfspace of an individual’s selfconcept of selfthe point of view of different conceptual approaches of national and foreign psychology. A.
Mariia Dryhus
doaj   +1 more source

The development of the five mini-theories of self-determination theory: an historical overview, emerging trends, and future directions [PDF]

open access: yes, 2010
Self-determination theory is a macro-theory of human motivation, emotion, and personality that has been under development for 40 years following the seminal work of Edward Deci and Richard Ryan.
Niemiec, Christopher P   +2 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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