Results 61 to 70 of about 989,825 (263)
UAV for monitoring the settlement of a landfill
European Journal of Remote Sensing, 2019 Remote-pilot aircraft are developing very rapidly and their potential in the various fields is often still to be fully investigated. The possibility to fly over the areas to be surveyed without the need to access the areas themselves makes the use of ...
Valerio Baiocchi +5 more
doaj +1 more source
Treatment of Malignant Glaucoma
Beyoglu Eye Journal, 2017 Malignant glaucoma is one of the most challenging conditions in ophthalmology. The exact etiology of this complication is not fully understood, and its management is usually challenging.
Cigdem Altan +2 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Book review – Wildlife Tourism Futures. Encounters with Wild, Captive and Artificial Animals [PDF]
Journal of Tourism Futures, 2021 Sabine Michaela Lehmann
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Hours worked of the self‐employed and agglomeration [PDF]
Growth and Change, 2018 AbstractThis paper investigates the causal effects of agglomeration on hours worked by the self‐employed. Urbanization and localization are instrumented using the minimum distance from the work Public Use Microdata Area centroid to the United States’ coastlines and estimated industry shares in 1930.
openaire +2 more sources
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Natural resources, tourism and community livelihoods in Southern Africa [PDF]
Journal of Tourism Futures, 2020 Sabine Michaela Lehmann
doaj +1 more source