Results 91 to 100 of about 265,155 (296)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Non-destructive testing techniques for the observation of healing effects in cementitious materials: an introduction [PDF]

, 2013
To develop an appropriate method of self-healing for cementitious materials including the right composition and amount of suitable healing agents it is required to investigate the healing efficiency for certain material mixtures.
De Belie, Nele, Grosse, CU, Van Tittelboom, Kim   +2 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Toughening Self‐Healing Elastomers with Chain Mobility

Advanced Science
Enhancing fracture toughness and self‐healing within soft elastomers is crucial to prolonging the operational lifetimes of soft devices. Herein, it is revealed that tuning the polymer chain mobilities of carboxylated‐functionalized polyurethane through ...
Matthew Wei Ming Tan, Patrick Michael Thornton, Gurunathan Thangavel, Hyunwoo Bark, Reinhold Dauskardt, Pooi See Lee   +5 more
doaj   +1 more source

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari, Caterina Costagliola, Marta Nebiolo, Francesca Parisi, Martina Morini, Katia Mazzocco, Gabriele Gaggero, Stefano Volpi, Stefania Sorrentino, Virginia Livellara   +9 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Humidity‐Induced Self‐Oscillating and Self‐Healing Hypercrosslinked Metal–Organic Polyhedra Membranes

Advanced Science
Designing autonomously oscillating materials is highly desirable for emerging smart material fields but challenging. Herein, a type of hypercrosslinked metal–organic polyhedra (HCMOPs) membranes formed by covalent crosslinking of boronic acid‐modified Zr‐
Jiamin Li, Zhaoyi Liu, Jinjin Liu, Xue Liu, Yang Luo, Jiajie Liang, Zhenjie Zhang   +6 more
doaj   +1 more source

Recent Advances of Self-Healing Materials for Civil Engineering: Models and Simulations

Buildings
Empowering materials with self-healing capabilities is an attractive approach for sustainable development. This strategy involves using different methods to automatically heal microcracks and damages that occur during the service life of materials or ...
Cen-Ying Liao, Lin Zhang, Si-Yu Hu, Shuai-Jie Xia, D. M. Li   +4 more
doaj   +1 more source

Synthesis of mechanically strong waterborne poly(urethane-urea)s capable of self-healing at elevated temperatures [PDF]

, 2019
Although various chemistries have been introduced into polyurethanes in order to obtain self-healing abilities, implementing these materials in applications requiring high strength is challenging as strong materials imply a limited molecular motion, but ...
Asua González, José María, Ballard, Nicholas, Fernández San Martín, Mercedes, Nevejans, Sil, Reck, Bernd, Rivilla de la Cruz, Iván, Santamaría Ibarburu, Pedro Antonio   +6 more
core  

Adaptive Fault Detection exploiting Redundancy with Uncertainties in Space and Time

, 2019
The Internet of Things (IoT) connects millions of devices of different cyber-physical systems (CPSs) providing the CPSs additional (implicit) redundancy during runtime.
Bartocci, Ezio, Grosu, Radu, Platzer, Michael, Ratasich, Denise   +3 more
core   +2 more sources