Results 81 to 90 of about 11,171,980 (304)

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

open access: yes
Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein   +11 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Bridging Language Challenges in Technology Teacher Education

open access: yesEducation Sciences
Technology teacher preparation is continuously evolving to stay relevant and responsive to the educational context of students and to bridge the theory–practice divide.
Adri Du Toit   +4 more
doaj   +1 more source

Self-learning Monte Carlo method

open access: yesPhysical Review B, 2017
Monte Carlo simulation is an unbiased numerical tool for studying classical and quantum many-body systems. One of its bottlenecks is the lack of general and efficient update algorithm for large size systems close to phase transition or with strong frustrations, for which local updates perform badly.
Liu, Junwei   +3 more
openaire   +5 more sources

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Parental involvement in homework to foster self-regulated learning skills: a qualitative study with parents from selected higher quintile schools

open access: yesCogent Education
The lack of parental involvement and poor self-regulation among learners have been identified as significant factors affecting the ongoing high rates of failure and dropout in schools situated in the lower socioeconomic strata.
Bernadette Geduld
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Guided Self Learning

open access: yesInternational Journal of Family Business and Management, 2019
In our days of Artificial Intelligence, smartphones and all Internet of Things that provide us with myriads of connected objects at a very early age, education has to be transformed to integrate the searching power these means of communications, in fact first of all means of exploration-incorporation, provide every single individual in our society ...
openaire   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

An Evaluation System for HVDC Protection Systems by a Novel Indicator Framework and a Self-Learning Combination Method

open access: yesIEEE Access, 2020
High voltage direct current (HVDC) is expected to bring forth large capacity, long transmission distance, and asynchronous grid interconnection. To quantitatively analyze the protection systems of HVDC, an evaluation system is proposed with a novel ...
Leijiao Ge   +5 more
doaj   +1 more source

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