Results 91 to 100 of about 4,518,436 (247)

Investigating self-concept and health-related quality of life

, 2006
Health-related quality of life has been an important topic of research in diverse fields such as medicine, nursing, community service provision and psychology.
Dowson, Martin, Martin, Andrew J., Martinez, Carissa J.   +2 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The measurement of multidimensional self-concept in adults with mild intellectual disability

, 2006
Although self-concept is now recognised as a multidimensional construct, unidimensional measurement is still common practise for adults with mild intellectual disabilities.
Craven, Rhonda, Martin, Andrew J., Dixon, Roselyn M.   +2 more
core  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Multifaceted self-concept of indigenous Australian secondary students : structure and relations to other academic variables

, 2006
In response to recent calls for the development of culturally relevant and applicable quantitative instruments for research into the educational disadvantages suffered by Indigenous Australian students, Bodkin-Andrews, Craven & Marsh (2005) analysed the ...
Craven, Rhonda, Bodkin-Andrews, Gawaian
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

The use of interactional metadiscourse markers by Saudi EFL male and female college students: the case of a gender-sensitive topic

Humanities & Social Sciences Communications
A few studies have explored the use of interactional metadiscourse markers in argumentative writing by male and female college students. More importantly, none explored the topic of metadiscourse resources with respect to gender-sensitive topics.
Ghuzayyil Mohammed Al-Otaibi, Abeer Abdulhadi Hussain   +1 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

A thug’s grub

The European Journal of Humour Research
Renaud Séchan (known as just “Renaud”) has been a particularly popular French singer-songwriter since the seventies. This success relies in part on the persona he builds of an angry, yet sentimental, small-time thug, and on a humorous language, including
Nils Couturier, Anne-Sophie Bories
doaj   +1 more source

Perceptions of family functioning and self-concept in adolescent anorexia nervosa

, 2006
Authors have highlighted the importance of the family for the development of positive self-concept and identity, not only in mental health research but also in various developmental and social psychology fields.
Halse, Christine, Ha, My Trinh, Marsh, Herbert W., Martin, Andrew J.   +3 more
core