Results 101 to 110 of about 4,518,436 (247)
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Research on school bullying tends to focus on single-item item rather than scale-based questionnaires, the former of which do not take into consideration the different types of bullying which can take place.
Finger, Linda R. +2 more
core
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Researchers often use promotional language (“hyping”) in scientific publications to draw attention to their findings. Here we examined whether promotional language is indeed associated with higher academic impact and public attention.
Olga Stavrova +3 more
doaj +1 more source
Current research indicates that a key to successful inclusive practices lies in teacher attitudes and preparation. It is proposed that effectively including students with disabilities in mainstream classrooms will be dependent on the focus and content of
Healey, Jean B., Marder, Kurt
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Department of Political Science Self Study Report for Academic Program ReviewDepartment of Political Science Self Study Report Academic Program ReviewDepartment of Political Science Self Study Report Academic Program ...
Academic Program Review, APR +2 more
core
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
The educational placement of students with mild intellectual disabilities remains controversial. Arguments for educational placement are often based upon the anticipated impact upon self-concept.
Tracey, Danielle K. (R13635) +1 more
core
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source

