Results 51 to 60 of about 37,649,734 (261)
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2013 Department of Political Science Self Study Report for Academic Program ReviewDepartment of Political Science Self Study Report Academic Program ReviewDepartment of Political Science Self Study Report Academic Program ...
Academic Program Review, APR +2 more
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2014 Religious Studies Program Self Study Report - Academic Program Review - 2014Religious Studies Program Self Study Report - Academic Program ReviewReligious Studies Program - Academic Program ...
Religious Studies Program, Self Study Report +1 more
core
Forsker-praktiker-samarbejde som et ligeværdigt videns- og læringsrum: Et didaktisk anliggende
Nordic Journal of Vocational Education and TrainingThis article explores collaboration between research, education, and practice in vocational education and training, framed as a knowledge triangle. The purpose is to offer insight into how knowledge triangle collaboration can be designed didactically to
Anne-Birgitte Nyhus Rohwedder +2 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Native American Studies Program APR Self Study
, 2014 Native American Studies Program Academic Program Review Self Study ReportNative American Studies Program Academic Program Review Self Study ReportNative American Studies ...
Native American Studies Program Academic Program Review Self Study Report, APR Self Study Report
core
Challenges and learning outcomes of educational design research for PhD students
Frontline Learning Research, 2016 Educational design research (EDR) is described as a complex research approach. The challenges resulting from this complexity are typically described as procedural, whereas EDR might also be challenging for different reasons, specifically for early ...
Larike H. Bronkhorst +1 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source