Results 91 to 100 of about 3,071,906 (311)

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin   +11 more
wiley   +1 more source

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos   +9 more
wiley   +1 more source

SELF-EDUCATION AND SELF-SUFFICIENCY

open access: yes, 2016
Preoccupied almost exclusively and permanently by the (current) problems of education, it seems that we forgot about the existence, significance and value of self-education in shaping human beings. Some even tend to exclude it, either identifying it with
Albu, Gabriel
core  

Food security and self-sufficiency as a factor of country’s sustainable development: assessment methods and solutions

open access: yesDiscover Sustainability
Objective A serious challenge of our time, threatening the whole of humanity, is the lack of food. The aggravation of this problem in many countries is caused by climate change, natural and man-made disasters, deterioration of the epidemiological and ...
Aizhan Tleuberdinova   +3 more
doaj   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru   +13 more
wiley   +1 more source

The Pitfalls of Work Requirements in Welfare-to-Work Policies: Experimental Evidence on Human Capital Accumulation in the Self-Sufficiency Project [PDF]

open access: yes
This paper investigates whether policies that encourage recipients to exit welfare for full-time employment influence participation in educational activity.
Riddell, Chris, Riddell, W. Craig
core  

Trial calculation of dining table self-sufficiency ratio : Consideration of self-sufficiency ratio from Hokkaido's dining table [PDF]

open access: yes, 2015
In this paper, using the dining table in Hokkaido as a case example, we calculated teh dining table self-sufficiency ratio as an indicator that recognizes the degree of local production for lacal comsumption. As a result, the Hokkaido's dining table self-
近藤, 巧, 坂下, 明彦, 吉本, 諭
core  

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

From Self-Sufficiency to Food Security. Notes on the Swiss Experimental Heritage

open access: yes
Through this lecture Elena Cogato Lanza presents the Swiss Plan Wahlen, a regime of intensive food production and food rationing, introduced during the Second World War in an effort to increase food self-sufficiency of the nation.
Cogato Lanza, Elena
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

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