Results 71 to 80 of about 4,976,813 (295)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Self-sufficiency of agriculture in Finland in 1970—1983
Agricultural and Food Science, 1986 This study is aimed at considering self-sufficiency and food security in Finland. Self-sufficiency of final products has been over 100 % for a long period. Only self-sufficiency of fruits and vegetables is below 100 % due to the climate. Self-sufficiency
Lauri Kettunen
doaj
Types and forms of the enterprise’s self-sufficiency demonstration
Проблеми теорії та методології бухгалтерського обліку, контролю і аналізу, 2021 The article investigates the essence of the concepts of types and forms of self-sufficient development of enterprises, proposes their main characteristics and conditions of economic activity.
М.I.
doaj +1 more source
Data center heated greenhouses, a matter for enhanced food self-sufficiency in sub-arctic regions
, 2021 This paper examines the possibility of increasing Northern Sweden’s degree of self-sufficiency in food supply, at the 65th latitude, by using a data center as a heating source for greenhouse production.
Hampus Markeby Ljungqvist +3 more
semanticscholar +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Long-Term Agricultural Development Problems of the Russian Far East [PDF]
Пространственная экономика, 2012 The article considers the problems of long-term agricultural development and prospects of scientifictechnical and technological modernization. The author justifies two versions of the perspective agricultural development and opportunities for the local ...
Grigory Isakovich Sukhomirov +1 more
doaj +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Agritech, 2019 Corn is one of five main commodities that is expected to achieve self-sufficiency at the end of RPJMN 2019. However, the gap between supply and demand capacities was still quite large, so that imports are still conducted.
Parama Tirta Wulandari Wening Kusuma +1 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source