Results 71 to 80 of about 20,005,903 (395)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Minimum entropy production by microswimmers with internal dissipation

Nature Communications, 2023
The energy dissipation and entropy production by self-propelled microswimmers differ profoundly from passive particles pulled by external forces.
Abdallah Daddi-Moussa-Ider, Ramin Golestanian, Andrej Vilfan   +2 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Mechanosensitive Self-Replication Driven by Self-Organization [PDF]

, 2010
Self-replicating molecules are likely to have played an important role in the origin of life, and a small number of fully synthetic self-replicators have already been described.
Belenguer, Ana M.,, Carnall, Jacqui M.A.,, Otto, Sijbren,, Peyralans, Jérôme J.-P.,, Stuart, Marc C.A.,, Waudby, Christopher A.,   +5 more
core   +3 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Persistent accelerations disentangle Lagrangian turbulence

Nature Communications, 2019
Particles in turbulence, as encountered in the atmosphere or the oceans, experience strongly varying local flow conditions over time. Bentkamp et al. show that this statistical complexity can be broken down into simpler parts, allowing for insights into ...
Lukas Bentkamp, Cristian C. Lalescu, Michael Wilczek   +2 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Review of Ann Murray, ed. Germanistik in Ireland, Interrogating Normalcy

Forum, 2014
Germanistik in Ireland, Interrogating Normalcy, edited by Ann Murray, is a rich and diverse collection of essays from postgraduate students within German Studies.
Lizzy Robinson-Self
doaj   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Seeking to improve criterion and construct validity of retrospective self-reports of physical activity with brief reporting periods and quantitative response scales

Scientific Reports
Self-reported information is central to many scientific fields and achieving high levels of validity for these data is paramount. Concerns have been voiced about the validity of retrospective self-reports because of possible distortion of recall by ...
Arthur A. Stone, Meynard Toledo, Stefan Schneider, Joshua Smyth, Doerte U. Junghaenel, Sarah Goldstein, Olivia Pomeroy   +6 more
doaj   +1 more source