Results 51 to 60 of about 3,241,760 (311)

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges   +12 more
wiley   +1 more source

Disaster Risk Reduction for Sustainable Development Goals [PDF]

open access: yesEuropean Project Management Journal, 2017
Our civilization is witnessing the devastating power of natural disasters all over the world. Unfortunately, it is evident that the number and intensity of disasters increased over time. Consequently, grate number of victims and material damage force the
Nataša Petrović   +2 more
doaj  

Implantable device actuated by manual button clicks for noninvasive self‐drug administration

open access: yesBioengineering & Translational Medicine, 2023
Self‐injectable therapy has several advantages in the treatment of metabolic disorders. However, frequent injections with needles impair patient compliance and medication adherence.
Cho Rim Kim   +11 more
doaj   +1 more source

Epac2 in midbrain dopamine neurons contributes to cocaine reinforcement via enhancement of dopamine release

open access: yeseLife, 2022
Repeated exposure to drugs of abuse results in an upregulation of cAMP signaling in the mesolimbic dopamine system, a molecular adaptation thought to be critically involved in the development of drug dependence.
Xiaojie Liu   +10 more
doaj   +1 more source

Adolescent D-amphetamine treatment in a rodent model of attention deficit/hyperactivity disorder: impact on cocaine abuse vulnerability in adulthood [PDF]

open access: yes, 2016
RATIONALE: Stimulant medications for attention-deficit/hyperactivity disorder (ADHD) in adolescents remain controversial with respect to later development of cocaine abuse.
Dwoskin, Linda P.   +3 more
core   +1 more source

Self-monitoring accuracy does not increase throughout undergraduate medical education [PDF]

open access: yes, 2020
Context: Accurate self-assessment of one's performace on a moment-by-moment basis (ie, accurate self-monitoring) is vital for the self-regulation of practising physicians and indeed for the effective regulation of self-directed learning during medical ...
Hautz, W., Kämmer, J., März, M.
core   +2 more sources

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

Deletion of the gabra2 gene results in hypersensitivity to the acute effects of ethanol but does not alter ethanol self administration [PDF]

open access: yes, 2012
Human genetic studies have suggested that polymorphisms of the GABRA2 gene encoding the GABA(A) α2-subunit are associated with ethanol dependence. Variations in this gene also convey sensitivity to the subjective effects of ethanol, indicating a role in ...
A Agrawal   +46 more
core   +2 more sources

Exercise decreases speedball self-administration [PDF]

open access: yesLife Sciences, 2014
Epidemiological studies report that individuals who exercise are less likely to abuse drugs. Preclinical studies report that exercise, in the form of treadmill or wheel running, reliably decreases the self-administration of psychomotor stimulants and opioids.
Ryan T, Lacy   +4 more
openaire   +2 more sources

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