Results 41 to 50 of about 3,241,760 (311)

Adolescent D-amphetamine treatment in a rodent model of ADHD: pro-cognitive effects in adolescence without an impact on cocaine cue reactivity in adulthood [PDF]

open access: yes, 2016
Attention-deficit/hyperactivity disorder (ADHD) is comorbid with cocaine abuse. Whereas initiating ADHD medication in childhood does not alter later cocaine abuse risk, initiating medication during adolescence may increase risk.
Dwoskin, Linda P.   +3 more
core   +1 more source

Intravenous self administration of mercury [PDF]

open access: yesQJM, 2008
A 24-year-old man attempted suicide by intravenous injection of elemental mercury. The exact quantity of injected elemental mercury was unknown. Five days later, the patient presented with painful erythema involving the anterior part of both forearms. On admission, laboratory findings disclosed the following: haemoglobin: 14.5 mmol/l, white blood cell ...
I, Marie   +5 more
openaire   +2 more sources

Deletion of the GABAA α2-subunit does not alter self dministration of cocaine or reinstatement of cocaine seeking [PDF]

open access: yes, 2014
Rationale GABAA receptors containing α2-subunits are highly represented in brain areas that are involved in motivation and reward, and have been associated with addiction to several drugs, including cocaine.
A Agrawal   +55 more
core   +1 more source

Simultaneous Quantification of Spatially Discordant Alternans in Voltage and Intracellular Calcium in Langendorff-Perfused Rabbit Hearts and Inconsistencies with Models of Cardiac Action Potentials and Ca Transients

open access: yesFrontiers in Physiology, 2017
Rationale: Discordant alternans, a phenomenon in which the action potential duration (APDs) and/or intracellular calcium transient durations (CaDs) in different spatial regions of cardiac tissue are out of phase, present a dynamical instability for ...
Ilija Uzelac   +7 more
doaj   +1 more source

The dual orexin receptor antagonist TCS1102 does not affect reinstatement of nicotine-seeking. [PDF]

open access: yesPLoS ONE, 2017
The orexin/hypocretin system is important for appetitive motivation towards multiple drugs of abuse, including nicotine. Both OX1 and OX2 receptors individually have been shown to influence nicotine self-administration and reinstatement.
Shaun Yon-Seng Khoo   +2 more
doaj   +1 more source

Nicotine self‐administration in rats [PDF]

open access: yesBritish Journal of Pharmacology, 1984
Female Wistar rats were allowed to self‐administer nicotine solutions through indwelling jugular vein cannulae for 23 h per day for periods from three to five weeks. Two response levers were available to the rats; responding on one lever, designated the active lever, produced an immediate infusion of nicotine solution or saline.
B M, Cox, A, Goldstein, W T, Nelson
openaire   +2 more sources

Compliance of the regulation of supervision over local government in the Polish Constitution and in legal acts

open access: yesКонституційно-правові академічні студії
The aim of the article will be to analyze the regulation of supervision over local government in the Polish Constitution and in the legal system regulating the supervision of local government.
Kazimierz Bandarzewski
doaj   +1 more source

Ukrainian Post-Communist Transformation: Causes, Consequences and Threats

open access: yesQuaestiones Geographicae, 2014
The post-communist transformation of Ukraine differs significantly from that of other countries of Central and Eastern Europe. First of all, Ukraine’s transition from totalitarianism to democracy has been long and still remains uncompleted.
Kuczabski Aleksander, Michalski Tomasz
doaj   +1 more source

Analyses of Self – Administration Reality of Central Sport Federation Presidents from Administrative Bureau Point of View in Iraq

open access: yesالتربية الرياضية, 2021
The importance of the research lies in self – administration being a modern topic in sport administration in general and in Iraqi central sport federation’s administration in particular.
Atheer Ailan Abdul Hussein   +1 more
doaj   +1 more source

Enhanced self-administration of the CB1 receptor agonist WIN55,212-2 in olfactory bulbectomized rats: evaluation of possible serotonergic and dopaminergic underlying mechanisms [PDF]

open access: yes, 2014
Depression has been associated with drug consumption, including heavy or problematic cannabis use. According to an animal model of depression and substance use disorder comorbidity, we combined the olfactory bulbectomy (OBX) model of depression with ...
Amchova P   +11 more
core   +1 more source

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