Methylphenidate treatment beyond adolescence maintains increased cocaine self-administration in the spontaneously hypertensive rat model of attention deficit/hyperactivity disorder [PDF]
Past research with the spontaneously hypertensive rat (SHR) model of attention deficit/hyperactivity disorder showed that adolescent methylphenidate treatment enhanced cocaine abuse risk in SHR during adulthood.
Baskin, Britahny M. +2 more
core +1 more source
BackgroundPrevious studies have shown that repetitive transcranial magnetic stimulation (rTMS) to the dorsolateral prefrontal cortex may serve as a potential treatment for cocaine use disorder (CUD), which remains a public health problem that is ...
Diana Martinez +8 more
doaj +1 more source
One-Stop Dispensing: Hospital Costs and Patient Perspectives on Self-Management of Medication
(1) Objective: To assess hospital medication costs and staff time between One-Stop Dispensing (OSD) and the Traditional Medication System (TMS), and to evaluate patient perspectives on OSD.
Morten Baltzer Houlind +7 more
doaj +1 more source
Are cocaine-seeking “habits” necessary for the development of addiction-like behavior in rats? [PDF]
Drug self-administration models of addiction typically require animals to make the same response (e.g., a lever-press or nose-poke) over and over to procure and take drugs.
Fadanelli, Monica +3 more
core +2 more sources
Cocaine self-administration in the mouse: A low-cost, chronic catheter preparation [PDF]
Intravenous drug self-administration is the most valid animal model of human addiction because it allows volitional titration of the drug in the blood based on an individual’s motivational state together with the pharmacokinetic properties of the ...
Brian Cadle +4 more
core +3 more sources
Neuroadaptations in the Cellular and Postsynaptic Group 1 Metabotropic Glutamate Receptor mGluR5 and Homer Proteins Following Extinction of Cocaine Self-administration [PDF]
This study examined the role of group1 metabotropic glutamate receptor mGluR5 and associated postsynaptic scaffolding protein Homer1b/c in behavioral plasticity after three withdrawal treatments from cocaine self-administration.
Ghasemzadeh, M. Behnam +4 more
core +2 more sources
Hypocretin-1 receptors regulate the reinforcing and reward-enhancing effects of cocaine: pharmacological and behavioral genetics evidence. [PDF]
Considerable evidence suggests that transmission at hypocretin-1 (orexin-1) receptors (Hcrt-R1) plays an important role in the reinstatement of extinguished cocaine-seeking behaviors in rodents.
Fowler, Christie D +3 more
core +3 more sources
Adolescent D-amphetamine treatment in a rodent model of ADHD: pro-cognitive effects during adolescence and cocaine abuse risk during adulthood [PDF]
Attention-deficit/hyperactivity disorder (ADHD) is comorbid with cocaine abuse. Whereas initiating ADHD medication in childhood does not alter later cocaine abuse risk, initiating medication during adolescence may increase risk.
Baskin, Britahny M. +5 more
core +1 more source
Computer assisted self and peer assessment: applications, challenges and opportunities [PDF]
This paper discusses self and peer assessment (SPA) using CASPAR (Computer Assisted Self and Peer Assessment Ratings) – a software tool designed to aid the administration of SPA.
Lugosi, Peter
core +1 more source
Generation Z in Search of Leadership - Model of Intergenerational Leadership for Creating Commitment (MILCC) [PDF]
Generation Z is integrating into the fast-changing work world. The effects of its entry are rapid employee turnover, perceptions of no commitment to organizations, and difficulty in understanding employee needs. This article presents a model for creating
Tidhar LEV
doaj +1 more source

