Results 11 to 20 of about 3,241,760 (311)

Intranasal cocaine self-administration in male mice [PDF]

open access: yesNature Communications
Intravenous drug self-administration has been widely used in behavioral neuroscience to model addiction and heightened motivational states; however, the technique is notoriously difficult and its utility has been in steady decline.
Kirsty R. Erickson   +9 more
doaj   +2 more sources

Astrocytes in the Ventral Tegmental Area Are Involved in Cotinine Self-Administration in Male Wistar Rats [PDF]

open access: yesBrain Sciences
Background: Our recent studies indicate that astrocytes in a key mesocorticolimbic region play an important role in nicotine reinforcement. Nicotine self-administration elevated the astrocyte marker glial fibrillary acidic protein (GFAP) in the nucleus ...
Xiaoying Tan, Zheng-Ming Ding
doaj   +2 more sources

Developing a novel tool to assess the ability to self-administer medication – A systematic evaluation of patients’ video recordings in the ABLYMED study

open access: yesFrontiers in Medicine, 2023
BackgroundOlder people often experience medication management problems due to multimorbidity, polypharmacy and medication complexity. There is often a large gap between patients’ self-reported and actual abilities to handle the self-administration of ...
Anneke Luegering   +11 more
doaj   +1 more source

Critical analysis of the achievements of the global millennium development goals and new approaches to sustainable development management [PDF]

open access: yesE3S Web of Conferences, 2020
This article provides a critical analysis of the achievements of human development towards sustainable development in the 17th Global Goals and reveals new approaches to the management of this process.
Lelechenko Anzhela   +3 more
doaj   +1 more source

Practical aspects of the use of antisipative management in the process of ensuring the economic security of an enterprise

open access: yesBusiness: Theory and Practice, 2021
Operating in an unstable market economy environment, enterprises can achieve success in business, provided that a system of economic security is created, focused on predicting possible changes in the internal and external environment using measures.
Andriy Shtangret   +4 more
doaj   +1 more source

Do entrepreneurial self-efficacy, entrepreneurial motivation, and family support enhance entrepreneurial intention? The mediating role of entrepreneurial education [PDF]

open access: yesAsia Pacific Journal of Innovation and Entrepreneurship, 2023
Purpose – Entrepreneurship is an important paradigm for enhancing the economic well-being of nations. However, despite heated debate about the significant role of entrepreneurial education (EE) in developing favourable entrepreneurial intention (EI ...
Oussama Saoula   +3 more
doaj   +1 more source

Evaluation of the implementation of the circular economy in EU countries in the context of sustainable development

open access: yesBusiness: Theory and Practice, 2020
The circular economy is interpreted as a stable economic system, which aims at eliminating the consequences and costs, as well as providing a constant cycle of necessary resources. That is why it is so important to conduct its assessment today.
Myroslav Kryshtanovych   +4 more
doaj   +1 more source

MODELING THE CYBERSECURITY OF THE SOCIO-ECONOMIC SYSTEM UNDER MARTIAL LAW

open access: yesФінансово-кредитна діяльність: проблеми теорії та практики, 2023
Industry 5.0 is already gradually beginning to manifest itself in various aspects of our lives. It is especially sensitive for ensuring socio-economic development.
Mykola Izha   +4 more
doaj   +1 more source

Taar1 gene variants have a causal role in methamphetamine intake and response and interact with Oprm1

open access: yeseLife, 2019
We identified a locus on mouse chromosome 10 that accounts for 60% of the genetic variance in methamphetamine intake in mice selectively bred for high versus low methamphetamine consumption. We nominated the trace amine-associated receptor 1 gene, Taar1,
Alexandra M Stafford   +9 more
doaj   +1 more source

Environmental enrichment facilitates cocaine-cue extinction, deters reacquisition of cocaine self-administration and alters AMPAR GluA1 expression and phosphorylation [PDF]

open access: yes, 2015
This study investigated the combination of environmental enrichment (EE) with cocaine‐cue extinction training on reacquisition of cocaine self‐administration.
Dhonnchadha, Brid Aine Nic   +5 more
core   +1 more source

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