Results 51 to 60 of about 5,284,803 (289)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The influence of L-arginine on the self-medication behaviour of Drosophila Melanogaster larvae
, 2013 The theory of self-medication works on the premise that sick animals will change their diet to incorporate food substances that are not part of their usual diet, that will cure or alleviate the disease.
Robertson, Elizabeth
core +1 more source
Inappropriate habits of antibiotic use among medical specialists and students in Vilnius
Acta Medica Lituanica, 2016 Introduction. The resistance to antibacterial drugs is an emerging worldwide problem. Numbers of inappropriate ways to use antibiotics contribute to this issue. Self-medication is one of them.
Artūras Barkus, Ingrida Lisauskienė
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Medication management in mental health: nurses’ perceptions of their work with service users and carers [PDF]
, 2014 Aim: This study aimed to ascertain registered mental health nurses’ perceptions of their role involving medication management interventions with clients and their carers.
Hemingway, Steve
core +3 more sources
Hall's journal of healthSelf-medication allows individuals to treat minor health issues without a medical prescription, facilitated by the availability of over-the-counter (OTC) medicines (May, L., Schaefer, M., & Tamburro, C., 2023). This practice requires healthcare professionals, particularly pharmacists, to play a key role in ensuring the safe and rational use of ...
Mota, Inês +5 more
+11 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Self medication practices in Pakistan
Journal of Bahria University Medical and Dental College, 2013 Self medication is defined as consumption of medicinal products by a person to treat self recognized disorders, symptoms, recurrent disease or minor health problems. Globally, self-medication has been reported as being on the rise.
Tahira zamir , Nasim Karim
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source