Results 51 to 60 of about 571,993 (303)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Inappropriate habits of antibiotic use among medical specialists and students in Vilnius
Acta Medica Lituanica, 2016 Introduction. The resistance to antibacterial drugs is an emerging worldwide problem. Numbers of inappropriate ways to use antibiotics contribute to this issue. Self-medication is one of them.
Artūras Barkus, Ingrida Lisauskienė
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Medication and symptom management in persons living with HIV. perceptions and collaboration of persons living with HIV, their close support persons and healthcare providers [PDF]
, 2009 Over the past two decades, developments in the treatment and monitoring of HIV Infection have radically reduced morbidity and mortality rates among those affected by it [1].
Nicca, Dunja
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Self medication practices in Pakistan
Journal of Bahria University Medical and Dental College, 2013 Self medication is defined as consumption of medicinal products by a person to treat self recognized disorders, symptoms, recurrent disease or minor health problems. Globally, self-medication has been reported as being on the rise.
Tahira zamir , Nasim Karim
doaj
Indian Journal of Community Medicine, 2013 Background: Kano State is the most populous state, and one of those states pronounced with the highest prevalence of drug abuse in Nigeria. However, there is lack of documented data to back the assertion.
Umar M Lawan +3 more
doaj +1 more source
Covid Chronicles: Medicines and Self-medication
, 2022 I have had stomach and digestion issues since I was young, but it was never really treated. The last time I took strong pain killers I suffered an allergic reaction.
Sara (Anonymous) (13948291)
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source