Results 61 to 70 of about 5,284,803 (289)

Self-medication and storage storage of antibiotics.

, 2022
Self-medication and storage storage of antibiotics.
Tagwa Faisal Mohamed Alsadig (12003895), Randa Ahmed Abdalrheem Altamih (12003889), Rayan Ibrahim Hamid Mohamed (12003892), Mohammed Eltahier Abdalla Omer (12003883), Osman Kamal Osman Elmahi (12003874), Ahd Alaaeldin Hussain Shareef (12003880), Mugahid Awad Mohamed Elmahi (12003886), Reem Abdalla Elsiddig Musa (12003877)   +7 more
core   +1 more source

Comparison of knowledge, attitude, practice and predictors of self-medication with antibiotics among medical and non-medical students in Tanzania

Frontiers in Pharmacology
Introduction: Self-medication with antibiotics (SMA) is a widespread problem in developing nations, including Tanzania.Methods: This study compared knowledge, attitudes, practices, and factors influencing antibiotic SMA among medical and non-medical ...
Lusajo Shitindi, Omary Issa, Baraka P. Poyongo, Pius Gerald Horumpende, Pius Gerald Horumpende, Pius Gerald Horumpende, Godeliver A. Kagashe, Raphael Z. Sangeda   +7 more
doaj   +1 more source

Pattern, awareness and perceptions of health hazards associated with self medication among adult residents of kano metropolis, northwestern Nigeria

Indian Journal of Community Medicine, 2013
Background: Kano State is the most populous state, and one of those states pronounced with the highest prevalence of drug abuse in Nigeria. However, there is lack of documented data to back the assertion.
Umar M Lawan, Isa S Abubakar, Abubakar M Jibo, Ahmed Rufai   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

On the Economics of Rational Self-Medication [PDF]

It has been established in the medical literature that self-medicating with imperfect information about either the use of a genuine or counterfeit drug or based on wrong self-diagnosis of ailment, which is predominant especially in developing countries ...
Wisdom Akpalu
core  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Emotional Distress May Increase Risk for Self-Medication and Lower Risk for Mood-related Drinking Consequences in Adolescents [PDF]

, 2012
The current study examines indicators of emotional distress and coping that may define sub-populations of adolescents at risk for two potential affect-related mechanisms underlying substance misuse: self-medication and mood-related drinking consequences.
Feagans Gould, Laura, Hersh, Matthew A., Matthew A. Hersh, Laura Feagans, Andrea M. Hussong, Hussong, Andrea M.   +5 more
core   +1 more source

Development of a new diabetes medication self-efficacy scale and its association with both reported problems in using diabetes medications and self-reported adherence [PDF]

, 2016
Betsy Sleath,1,2 Delesha M Carpenter,1 Susan J Blalock,1 Scott A Davis,1 Ryan P Hickson,1 Charles Lee,3 Stefanie P Ferreri,4 Jennifer E Scott,5 Lisa B Rodebaugh,6 Doyle M Cummings6,7 1Division of Pharmaceutical Outcomes and Policy, UNC Eshelman School ...
Hickson RP, Carpenter, Delesha M., Scott, Jennifer E, Rodebaugh, Lisa B, Carpenter DM, Sleath, Betsy, Davis SA, Lee C, Hickson, Ryan P., Ferreri, Stefanie P., Blalock SJ, Lee, Charles, Rodebaugh, Lisa B., Sleath B, Davis, Scott A, Davis, Scott A., Blalock, Susan J., Rodebaugh LB, Cummings, Doyle M., Blalock, Susan J, Scott JE, Ferreri SP, Scott, Jennifer E., Cummings DM, Hickson, Ryan P, Ferreri, Stefanie P, Carpenter, Delesha M   +26 more
core   +1 more source