Results 81 to 90 of about 5,284,803 (289)
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Self-medication patterns among Libyan University Medical students
Self-medication, the practice of using medications without professional guidance, is a significant public health concern globally, particularly among medical students who, despite their pharmacological training, often engage in this practice at high ...
Ahmed E. Atia
core +1 more source
Automedicación de analgésicos y antibióticos en estudiantes de pregrado de medicina
Medicina U.P.B., 2017 Objetivo: automedicación es el uso de productos medicinales sin prescripción médica. En estudiantes de medicina es una práctica común y puede asociarse con efectos adversos. El objetivo del presente trabajo fue determinar la prevalencia de automedicación
Marie Claire Berrouet Mejía +2 more
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
GAMBARAN SWAMEDIKASI PENGGUNAAN TANAMAN OBAT DI DESA SUNGAI GAMPA ASAHI
JIIS: Jurnal Ilmiah Ibnu Sina, 2016 Medicinal plants, known as herbal remedies have been used since time immemorial for generations to self medication. Self medication is an attempt self-medication using drugs, traditional medicine, or the traditional way without the guidance of experts ...
Ratih Pratiwi Sari
doaj
HIV-1 protease inhibitory effects of medicinal plants used as self medication by AIDS patients [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2003 Thirty-six chloroform-, methanol-, and water- extracts of some plants used as self mediciation by AIDS patients were investigated for their HIV-1 protease (HIV-1 PR) inhibitory activities.
Sopa Kummee +2 more
doaj
GAMBARAN PASIEN GERIATRI MELAKUKAN SWAMEDIKASI DI KABUPATEN SLEMAN
Pharmaciana, 2013 The increase in life expectancy caused geriatric population is also increasing. Geriatric patient is identical to the decline in physiological function that can lead to various diseases.
Woro Supadmi
doaj +1 more source
Self-Medication Behavior: Self-Medication Behavior
Journal of Midwifery and Nursing, 2020 In developing countries self-medication behavior is something that is very often found. This happens because self-medication behavior provides a cheaper and easier alternative for the community. Coupled with the ease in purchasing drugs. Self-medication is usually done to overcome complaints and minor illnesses that are often experienced by the ...
openaire +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source