Results 71 to 80 of about 5,482,341 (261)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

On the Economics of Rational Self-Medication [PDF]

open access: yes
It has been established in the medical literature that self-medicating with imperfect information about either the use of a genuine or counterfeit drug or based on wrong self-diagnosis of ailment, which is predominant especially in developing countries ...
Wisdom Akpalu
core  

Emotional Distress May Increase Risk for Self-Medication and Lower Risk for Mood-related Drinking Consequences in Adolescents [PDF]

open access: yes, 2012
The current study examines indicators of emotional distress and coping that may define sub-populations of adolescents at risk for two potential affect-related mechanisms underlying substance misuse: self-medication and mood-related drinking consequences.
Feagans Gould, Laura   +5 more
core   +1 more source

Characteristics of self-medication practice among self-medicated people.

open access: yes, 2022
(A) representing how often respondents self-medicated; (B) representing the different sources of self-medication where X-axis indicates the percentage of population and Y-axis indicates sources of medication; (C) representing the most common self ...
H. M. Hamidullah Mehedi (12082844)   +12 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The Correlation Between Medication Self-Management with Rational Medication Use Self-Efficacy and Medication Literacy in Patients with Stroke [PDF]

open access: yes
Zhimin Liu,1,2,* Xingyao Lu,2,3,* Yunyun Li,2,4 Yanfang Luo,1 Fen Ye,1 Renjuan Sun5 1Department of Neurology, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu Province, People’s Republic of China; 2Wuxi School of Medicine, Jiangnan ...
Liu Z, Li Y, Lu X, Sun R, Luo Y, Ye F
core  

Are attitudes towards medication adherence associated with medication adherence behaviours among patients with psychosis? A systematic review and meta analysis [PDF]

open access: yes, 2013
Background Studies have shown patient attitudes to be an important predictor for health related behaviours including medication adherence. It is less clear whether patient attitudes are also associated with medication adherence among patients with ...
McCabe, R.   +5 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Self-medicating scale. Outcomes measurement tool: drug use behaviour – self-medication .

open access: yes, 2008
This scale measures people’s beliefs about self-medication. It measures reluctance to self-mediate, ease of self-medication and beliefs about letting things run their ...
French, David P, James, Delyth H
core  

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