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Effect of Semaglutide and Empagliflozin on Pulmonary Structure and Proteomics in Obese Mice
Yu Yang,1,2 Xiaoyu Pan,1,3 Shuchun Chen1,3 1Department of Internal Medicine, Hebei Medical University, Shijiazhuang, People’s Republic of China; 2Department of Pharmacy, The Second Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of ...Pan X, Yang Y, Chen Score Peri‐operative glucagon‐like peptide‐1 receptor agonist use and outcomes: a national prospective multicentre cohort study
Anaesthesia, EarlyView.Summary Introduction
Peri‐operative glucagon‐like peptide‐1 receptor agonist (GLP‐1 RA) use is associated with delayed gastric emptying. It is unclear what proportion of patients having anaesthetic care are receiving GLP‐1 RAs; what strategies are used in their peri‐operative management; and whether the incidence of pulmonary aspiration and/or ...Thomas E. Potter, John N. Cronin, Justin Kua, Sophie Bloomfield, Mayur Murali, Frances Beatty, Andrew McKechnie, Danny J. N. Wong, Kariem El‐Boghdadly, on behalf of the GLIMPSE Resident Research Networks and Collaborators, Emily Beckett, Jessica Summers, Ellen Gorman, Abigail Brady, Chloe Butel, David Carter, Hei Chan, Rachel Elwood, Alexandra Gosling, Sarah Higgi, Katie MacNaughton, Radharetnasivan Meiarasu, Ellie Morgan, Emily Ratford, Nick Roberts, Sam Smith, Samuel Smith, Abigail Townsend, Helen Williams, Tom Woodhouse, Isabel Griffiths, Mohamed Hussein, Matilda John Ravindran, Joe Joseph, Matthew Sinnott, Sonia Andleeb, Jana Balogova, Sameera Fernando, Elizabeth Hardman, Adedoyin Ilesanmi, Chinmayi Kattimani, Prachi Nisar, Sanjay Sakholiya, Dristi Sharma, Victor Ade‐Davis, Hamza Anwar, James Bigley, Beata Biro, Rhiannon Brignall, Yousef Eltuhamy, Bhavesh Gohil, Anand Krishna, Shilpee Kumari, Jack Lu, Grace Newton‐Livens, Olanrewaju Kazeem, Madeleine Payne, Toby Reynolds, Rosanna Sasson, Henry Somers, Katy Surman, Francois Taljard, Eloise Wilson, Rama Aubeeluck, Reardon Jeffries, Kiran Mehta, Charlotte Moss, Michael Standen, Jebu Thomas, Toska Ukaj, Nidhi Vedd, Judith Wilson, Rachael Allen, Luke Auterson, Anne Bailey, Aideen Casey, Christine Clarke, Michael Crowe, Lauren Crozier, Melissa Flynn, Michael Getty, Ellen Gorman, Fergal Grannell, Laura Gray, Lynsay Greer, Brendan Haughey, Rosemary Hogg, Bhalwel Iqbal, Sagitha Joseph, Ewan Martin, Joanna McAteer, Jennifer McCann, Sarah McCann, Anna McCloy, Rachel McKee, Nicholas McNaughton, Emma McQuillan, Anjum Raheel, Hossam Abdelmotaal, Dominic Barton, Billy Holt, Richard Pugh, Jamie Scriven, Linda Warnock, Adarsh Aji, Maria Hussain, Amelia Kalwajtys, Lydia Meighen, Simon Mills, Sean Wynn, Anna Biggins, Rachael Brennand, Saxon Burnett, Jamie Clarke, Kiran Hassan, Dana Khoshnaw, Emily Langford, Andrew McKendry, Shaminder Kaur Olney, Rhean Rymell, Craig Smith, Rebecca Walford, Adam Windle, Benjamin Booker, Annabelle Crouch, Claudia Esquirol, James Hollamby, Danielle Huckle, Thomas Loka, Dominic Manetta‐Jones, Deborah Mann, Amy Matthews, Thomas Parry, James Perring, Ishani Sinha, Oliver Thomas, Molly Timlin, Thomas Wand, Zach Wardle, Lauren Warrington, Rosie Watts, Megan Williams, Sylwia Bartoszewicz, Khristianne Greenhalgh, Hannah Greensmith, Judy Havinga, Tanya Jayawardena, Josh Wall, Sophie Wouters, Katherine Woods, Sundar Ashok, Eleanor Cartwright, Amie Desancha, Genevieve Lawrence, Michael Masucci, Mitul Patel, Shirley Zhang, Katharine Barr, Mark Futcher, Christine Garner, Mehtaab Johal, Bradley Postill, Hannah Atkins, Nick Hooper, James Lumb, Molly Mercurio, Charlotte O'Driscoll, Nick Riddler, Sally Roscoe, Deepa Sannakki, Kamal Sayes, Jie Tan, James Wheeler, Matt Williams, Hoda AbouGhoneim, Philip Blackie, Lucy Connolly, Hikkaduwe Liyanage Priyangani Dharmapala, Ahmed Hassan, Samuel Hutchinson, Nandhini Joseph, Rito Kapoor, Evelyn Ledwidge, Edward Parkinson, Uma Patel, Niamh Sargeant, Garpagalakshmi Selvamani, Mia Sheikh, William Sloper, Heledd Thomas, Mohammed Akuji, Ayesha Danayal, Jack Doherty, Eleanor Gunn, Thomas Hubberstey, Robyn Mclean, Marrigje Nell, Jack Warbey, Sinan Bahlool, Jessica Bowen, Hugh Dalton, Mark Higgins, Alice Hipsey, Marten Lau, Milind Bhagwat, Gargee Bhatt, Aditya Bidi, Asmaa Hassan, Gianfranco Messina, Ashraf Motawea, Akshita Nagpal, Hima Nambiar, Radhika Patel, Henna Sattar, Yunus Sheikh, Niketa Shukla, Jithu Subhash, Arlin Thomas, Paraskevi Tsiotsi, Saad Zangie, Kate Kendrick, Simran Mann, Fergus Newing, Camilla Pople, Manav‐Vikram Singh, Rebecca Thorne, Owen Duffey, Grace Hillsmith, Matthew Judd, Rachael Lucas, Rebecca Pease, Nicola Powley, David Smith, Benjamin Magnus, Haripriya Rayasam, Jessica Wills, Himali Vitharana, Phoebe Owen, Louise Aaron, Anila Basheer, William Gatfield, Alex Gittens, Hannah Glatzel, Katie Keen, Roland King, Freddie Kirk‐Patrick, Laura Arnott, Joanne Mullender, Gemma Talling, Isobel Thornton, Lucy Williams, Thomas Woodland, Samuel Chequer, Urmila Cockerill, John Cronin, Jedd Da'Costa, Chantelle Gasa, Arhaan Haridas, Sophie Hetherington, Harjot Kaur, Mehakdeep Kaur, Aadya Khatuwala, Chrysostomos Kkamaris, Alexandra Munro, Arjun Nirmal, Nayan Perera, Thomas Potter, Thomas Reed, Suhani Shrestha, Thomas Collyer, Benjamin Huggon, Jack Sherlock, Matthew Smith, Chloe Start, Jasmine Wilkinson, Jack Willis, Steven Worthington, Kerri Clarke, Osayamen Iyekekpolor, Nicholas Moore, Lloyd Brown, Allen George, Rose Lefley, Stephen McAleer, Paul Parker, Joseph Simpkin, Rachel Turner, Gareth James, Aashika Luintel, Adam Ryan, Alun Thomas, Patrick Doyle, Isabelle Ferarrio, Jennifer Illingworth, Sana Iqbal, Somalia Mukherjee, Saaman Neriman, Catherine Onuorah, Anna Preston, Adam Savage, Kathryn Singh, Sanooj Soni, Joel Sugarman, Sophie Tillman, Drew Walker, Harshana Wilgamuwa, Janani Yogeswaran, Zahra Choudhury, Eleanor Dooley, Nosaiba Ezzelarab, Daveena Meeks, Sofia Peacock, Adam Davies, Thomas Hall, Sophia Khaleeq, Rachel Simper, Katie Turley, William Turner, Georgia Vellacott, Meg Barker, Ella Billson, Ian Chadderton, Elinor Clark, Edward Creamer, Frederick Glover, Sarah Goellner, Matthew Gowshall, Samuel Gregory, Lucy Gurr, Isabelle Haley, Henry Hill, Cynthia Ise, Sana Jaan, Amy Johnstone, Vikas Kaura, Matthew Laughton, Matthew Long, Daniel Maloney, Sarah Marsden, Khine Maung, Zahra Mohammed, Liam Murphy, Georgina Mussell, Abby Nicholas, Matthew Peakman, Priya Shankar, Madhurima Sinha, Michael Tattersfield, Caroline Thomas, Sophie Thompson, Emma Walshaw, Henry Wigfull, Adam Ahmad‐Edwards, Mawahib Ahmed, Adam Beebeejaun, Richard Breeze, Natalie Cameron, Preeya Chakraborty, Kimberly Cheah, Nighat Churghtai, Jonathan Drake, Conor Gibson, Sanjit Naskar, Eliot Siggs, Benedicte Sjoflot, Leana Sumagang, Caroline Yeldho, Daniel Akam, Sandor Bako, Ellen Collinson, Elias Delis, Samantha Dolan, Nick Greenwood, O'Baird Haider, Alexander Isted, Aneela Jahangir, Toby Kitching, Deepankar Majumdar, Ahmed Mohamed, Thomas Moore, Cath Robinson, Samuel Smith, Alexander Vidouris, Maaz Younus, Pavol Palcovic, Dan Sumner, Emilia Ardelean, Elin Barham, Alveena Bilal, Tushar Dixit, Samuel Graham, Rebecca Paterson, Luke Singer, Elin Barham, Clare Buffery, Jessica Cheung, Rachael Faulkner, Samuel Graham, David Lean, Rebecca Paterson, Jennifer Reynolds, Linda Skelly, Philippa Sturgess, Sarah Thornley, Matthew Gentle, Clare Hannah, Sarah Thornley, William Colyer, Thomas Hardwick, Danielle Hill, Elizabeth Hope, Shyam Moudhgalya, Brian Mwangi, Robert Palin, Lucy Pangbourne, Andrew Parrish, Rachel Peacock, Brendan Sloan, Jack Stephenson, Hannah Waheed, Ellen Wisnia, Brett Doleman, Rebecca Gill, Catherine Kitchen, Ryan McCrorie, Eoghan Meaney, Holly Morrison, Rory Sculthorp, Rebecca Thomas, Jennifer Willder, Emma Bailey, Katie Barbour, Rebecca Ivens, Katie Linden, Emma Murphy, Michael Ashfield, Susan Chapman, Ahmed Elshaer, Ayesha Khan, Hamish Matthews, Christopher Perman, Rachel Phillips, Pavan Raju, Joanna Simpson, Katie Watson, Douglas Young, Emma Bradley, Matthew Bridge, Meg Brocken, Megan Brocken, Clare Buffery, Jessica Cheng, Elizabeth Foulkes, Susie Fraser, Arthur Gallimore, Kiran Gowda, Linda Klimesova, Daniel Murphy, Adam Old, Nadia Paes, Richard Ramsaran, Hannah Regan, Jennifer Reynolds, Jaszmin Singh, Fatima Tu Zahra, Imogen Watkins, Jonathan Archer, Catherine Cook, Amy Dodd, Andrew Fitzsimons, George Keal, Justin Kirk, Rachel Lee, Ryan Nolan, Juliette Scriven, Thomas Sharp, Mark Zimmerman, Ahmed Elsayed, Peter Gadelsyed, Raju Jadhav, Monojit Paul, Manjunath Prashanth Sreenivasiah, Pei Shan Lim, Theo Clarke, Guilherme Correa, Shivali Dawda, Satvik Desai, James Hunter, Shaan Hyder, Hariharan Kavanoor Sridhar, Sonia Khan, Mathun Kuganesan, Tasneem Ladha, Elizabeth Lee, Su‐Vern Lim, Dipak Makanji, Ibrahim Nasr, Rohini Rajendran, Chiraag Shrinivas, Harjot Singh Punia, Gokula Sundaran, Tom Cox, Katherine Livesey, Alaa Nasir, Susan Baird, Maria Harkin, Emma Irvine, Claire Orr, Peter Pereira, Paula Pyper, Charlotte Spiers, Nauman Akhtar, Koushik Deb, Ellie Hezel, Abigail Minton, Atideb Mitra, Michaela Monaghan, Mohammed Rageh, Venkatesh Ramakrishnan, Maya Shah, Omkar Upputuri, James Winstanley, Mike Blundell, Emma Ladlow, Magde Albarade, Rosanna Baker‐Wilding, Marika Blackham, Ajish Cheruvathur, Natalie Edwards, Ahmed Elfaioumy, Tom Fletcher, Shanu George, Zakiya Maryam, Sindhu Sridhar, Dinesh Suryanarayanarao, Ashleigh Wood, Sheena Cheung, Joseph Gallaher, Naomi Lucas, Sophie Ragbourne, Tim Vorster, Mubashar Asif Bhatti, Edward Costar, Stephanie Edmunds, Sim Gill, Zubair Khalif, Duncan Paterson, Harriet Perkins, Elizabeth Ramsay, James Reilly, Ismail Ahmad Shaikh, Sameh Ahmed, Helen Bowes, Oliver Eastwood, Samiha Ismail, Sayali Khandekar, Annabel Ottilie Lloyd‐Thomas, Clare Morkane, Christopher Ng, Alexkumar Patel, Alice Roberts, Rohit Rohit, Sagar Saha, Laura Shepherd, Pooja Singh, Sibthein Khalid, Rotimi Latinwo, Prasan Panagoda, Maya Sussman, Hassan Abdullah, Sarah Clayton, Ahmad Daebis, Christopher Jennings, Nomonde Laxa, William Rea, Wael Zghaibe, Tim Cook, William Harper, Stuart Joy, Grace Kirby, Savinda Liyanagedera, Hannah Maxfield, Oliver Arscott, Xantha Holmwood, George Jones, Fariba Rezai, Michael Ashfield, Susan Chapman, Ahmed Elshaer, Ayesha Khan, Amy Ma, Hamish Matthews, Christopher Perman, Rachel Phillips, Pavan Raju, Joanna Simpson, Katherine Watson, Douglas Young, Luke Addison, Qumbar Ali Raza, Jonathon Ashworth, Eric Brook, Tess Cleg, Martin Diacon, Mark Dodd, Idris Elghazali, Michael Elliott, Jon Emberey, Rohan Farrimond, Colaco Rohan John Francis Ronald Harris, Zoë Gabriel, Carenza Glithero, Aaron Hall, Jessica Hartley, Anil Hormis, Sam Horton, Joshua Hulman, Muhammad Anser Javed, Rebecca Joy, Sumit Kumar, Vinayak Kumar, Tomas Macik, Jon Madeiros, Hadeer Mahmoud, Jason Mann, Saloni Mehta, Rohan Mishra, Jenny Mullan, Amanda Nair, Anna Nakamura, Darren O'brien, Georgia Oakes, Jean Ong, Paul Pharoah, Sailaja Pothuneedi, Sophie Prestidge, Atia Qaiser, Morwenna Read, Louis Rose, Steve Rowe, Owais Mushtaq Shah, Rosie Simmons, Nathan Sloane, Nick Smith, Robert James Smith, Alison Stainsby, Manoj Subramaniam, Niharika Thakur, Ben Thorp, Sara Tomassini, Naomi Ward, Catriona Webb, Anna Wilkins, Oliver Crowther, Alex Hunter, Gamunu Ratnayake, Alex Roney, Chris Vaz, Henry Sergeant, Clare‐Rose Agnew, Cara Boland, Ciara Casey, Christopher Cox, Seamus Crumley, Emma Gardiner, Ciara Mitchell, Charlotte Anderson, Tom Ballance, Rosanna Crabb‐Lahei, Guy Foggitt, Jodi Gaston Ross, Dalena Mathew, Kieran Purchase, Amy Sudworth, Lucy Tunn, Patrick Wastling, Rory Andelic, Gayle Dent, Jack Kavalier, Megan McLean, Philip McLean, Jonathan Emberey, James Arrowsmith, Conor Cruickshank, Anika De Silva, Carlo Ferrazzano, Matthew Gillen, Ciara Hamilton, Ashleigh Johnstone, Ben Knox, Emma Murray, Lisa Patterson, James Trouton, Matthew Wilson, Chloe Ablett, Matthew Cronin, Daniel Hodgin, Erin Prince, Arif Suleiman, William Twist, Amy Walkley, Ruth Haines, Linda Chan, Matthew Cole, Catherine Cromey, James Ellis, Luca Galvani, Tristan Hawkins, Helen Iliff, Thomas Imrie, Rowan Lo, Nicholas Palfrey, Gwilym Preest, Alex Roberts, Alexandra Sinclair, Kristian Thomas, Jack Williams, Jack D'Cruz, Buddug Eckley, Eve Hawley, Lowri Hughes, Callum Jennings, Linda Skelly, Sangeetha Balasingam, Charlotte Cleasby, Ankita Deshpande, Adam Longley, Zahra Mohamed, Zoe Rosenheim, Natalia Skorupska, Jennifer Thomson, Neil Verma, Emma Andrews, Daniel Butler, Brett Coleman, Olivia Creswell, Thomas Foley, Alison Gordon, Dave Levy, Saoirse Lyons, James Norton, Samuel Wenham, Emma Abbott, Taranpreet Bhoday, Lucy Blair, Sophie Boles, Nyssa Comber, Jack Fisher, Emma Grace, Rachel Grant, Isabel Greaves, Gemma Hodson, Manas Kubal, Stephanie Kwok, Konstantinos Mastorakis, Yasmine Samaroo, Duncan Wagstaff, Michael Webb, Soumia Abouzied, Tim Browning, Lucy Charig, Mark Edwards, Anive Grewal, Alec Hamilton, Oscar Hardy, Patrick Hayes, Jenny Heath, Catherine Jordan, Louise Mallam, Frances Ng, Charlotte Thomas, Lucy White, Katherine Whitley, Stephanie Worrall, Abdel Aziz Younes Ibrahim, Steven Coulson, Richard Fenton, John Hickman, Sarah Jackson, Tom Searle, Aashkaben Shah, Imogen Smith, Olivia Craig‐McFeely, Will Denehan, Abdelrahman ElGamal, Ramy Khalil, Robyn Lee, Hannah Theobald, Jack West, Robert Wiltshire, Amy Yeoman, Jeremy Fabes, Felix Flechtner, Robert Kirby, Rachel Atkinson, Alice Ball, Natalie Bell, Fraser Cohen, Oscar Freund‐Williams, Oliver George, Stephen Grant, Sarah Hodge, Marc Leach‐Tuite, Sarah Leatham, Raphael Levy, Rupert Mason, Charles Orr, Jonas Schlautmann, Nazia Siddiqui, Amrik Virdi, Eleri Clarke, Brett Doleman, Gabrielle Harrison, Michael Jarvis, Sofia Korre, Olivia Lambourne, Jessica Shepherd, Shalini Sriemevan, Fahad Zahid, Sakshi Beotra, Gabrielle Budd, Faiza Buhari, Kodithuwakku A Ramya Dissanayake, Achese Inimgba, Anamika Kansal, Kaushik Makam, Gautam Pati, Meenal Rana, Varu Senanayake, Zahra Siddiqui, Manpreet Singh, Jenq Uei Tan, Vishal Ashokkumar Unadkat, Chamika Wanigasundara, Suhao Yap, Rachael Faulkner, Shehla Shakooh, Tom Woodhouse, Andrew Carmichael, Anna Darling, Ashleigh Gillanders, Simon Smith, Timothy Spence, Joseph Carey‐Jenkins, Zoe Demetriou, Lauren Huyton, Tobias McGregor, Amy Spicer, Ann Biju, Jasper Craib, Ryan Davies, Jenny Edwards, Ross Leigh, Matthew Boyle, Rhys Broughton, Ben Chandler, Georgina Chapman, Eric Chiang, Matthew Eardley, Sumaya Liban, John O'Rourke, Callan Robinson‐Lynch, Murray Williams +862 morewiley +1 more sourceSemaglutide exerts neuroprotective effects by blocking the interleukin-17/NOD-like receptor family pyrin domain containing 3-mediated neuroinflammation pathway after traumatic brain injury
Neural Regeneration ResearchSemaglutide, a long-acting glucagon-like peptide-1 receptor agonist, exhibits significant neuroprotective effects in stroke and neurodegenerative diseases.Bin Zhang, Lu Kong, Yumei Wang, Wei He, Mengshi Yang, Xueling Zhang, Xiyu Chen, Yaxuan Zhang, Baiyun Liu, Miao Bai, Guangzhi Shi +10 moredoaj +1 more sourceSemaglutide Effect on Working Memory
Obesity is correlated with a number of negative health consequences (Fruh, 2017). Thus, researchers have investigated a variety of treatments that might reduce obesity levels. Semaglutide, under the brand name Ozempic, is a new popular drug that has well-Lu, Tommycore +1 more sourceThe Impact of Common Medications on Male Fertility: An Updated Systematic Review
Andrology, EarlyView.ABSTRACT Background
Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin +7 morewiley +1 more sourceTiming and duration of glucagon‐like peptide‐1 receptor agonist use and risk of nonarteritic anterior ischaemic optic neuropathy
Acta Ophthalmologica, EarlyView.Abstract Purpose
To investigate the association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) use and nonarteritic anterior ischaemic optic neuropathy (NAION) in type 2 diabetes, examining treatment recency and cumulative duration. Methods
This nationwide registry‐based nested case–control study utilizedz Danish health registries (1996 ...Siar Niazi, Filip Gnesin, Baker Nawfal Jawad, Zia Niazi, Puriya Daniel Wuertz Yazdanfard, Anne P. Toft‐Petersen, Kathrine Kold Sørensen, Amani Meaidi, Yousif Subhi, Christian Torp‐Pedersen +9 morewiley +1 more source
