Results 111 to 120 of about 20,698 (251)
Alimentary Pharmacology &Therapeutics, EarlyView.Metabolic dysfunction‐associated steatohepatitis is the second commonest US indication for liver transplantation but remains largely undiagnosed and untreated. Fibrosis stage is the strongest predictor of major adverse liver outcomes, with decompensation rates and transplant‐free survival diverging sharply between F3 and F4, while cardiovascular ...
Malek Ayoub +2 more
wiley +1 more source
Beyond fat: Does semaglutide affect lean mass?
This opinion paper aims to discuss the influence of semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), on lean mass beyond its impact on weight loss.
Tannaz, Jamialahmadi +6 more
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The Moral (Un)Desirability of New Biomedical Technologies as Potential Techno‐Fixes
Bioethics, EarlyView.ABSTRACT The techno‐fix argument, used to argue against technological interventions that address the consequences of social problems instead of their underlying causes, is increasingly invoked in biomedical discussions. However, especially in biomedicine, the techno‐fix argument remains conceptually underdeveloped.
Lieke van Kempen +2 more
wiley +1 more source
Molecular MetabolismObjective: The development of glucagon-like peptide-1 receptor (GLP-1R) agonists for the treatment of type 2 diabetes and obesity has been accompanied by evidence for anti-inflammatory and cytoprotective actions in the heart, blood vessels, kidney, and ...
Leticia Forny Germano +8 more
doaj +1 more source
Semaglutide and COVID-19 mortality risk
Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, is used to treat type 2 diabetes and manage weight in individuals with obesity or who are overweight. Semaglutide was found to reduce COVID-19-related mortality risk in a secondary analysis
Benjamin F. Arnold +2 more
core +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
Cosmetic Considerations of Semaglutide
Semaglutide-induced facial changes, or “Ozempic face” popularized by media, have gained increasing recognition since the widespread and growing use of Ozempic (semaglutide) for weight loss. It refers to facial volume depletion and soft tissue
Vijay Patel +3 more
core +1 more source
British Journal of Pharmacology, EarlyView.Abstract Gastric inhibitory polypeptide (GIP)/Glucagon‐like peptide‐1 (GLP‐1) receptor agonists are increasingly prescribed for the management of obesity and type 2 diabetes, yet research pertinent to their effects on muscle health is limited. Considering the central role of muscle strength as a sarcopenia component, this article summarizes emerging ...
Konstantinos Prokopidis
wiley +1 more source
Scientific ReportsDiabetic encephalopathy is a chronic neurodegenerative complication of diabetes mellitus characterized by cognitive decline, neuroinflammation, oxidative stress, and impaired insulin signaling. Semaglutide, a glucagon-like peptide-1 receptor agonist, has
Mohamed M. Zeweil +11 more
doaj +1 more source
Aurélie Mailhac,1 Lars Pedersen,1 Anton Pottegård,2 Jens Søndergaard,3 Torben Mogensen,4 Henrik Toft Sørensen,1 Reimar W Thomsen1 1Department of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark; 2Clinical ...
Pottegård A +6 more
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