Overexpression of Semaphorin 3A is a Marker Associated with Poor Prognosis in Patients with Nasopharyngeal Carcinoma. [PDF]
Imoto T +13 more
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Influences of Semaphorin 3A Expression on Clinicopathological Features, Human Papillomavirus Status, and Prognosis in Oropharyngeal Carcinoma. [PDF]
Pham HT +13 more
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Semaphorin 3A (SEMA3A); neuropilin 1 (NRP1) [PDF]
openaire +1 more source
Negative regulation of platelet function by semaphorin 3A.
KASHIWAGI, Hirokazu, TOMIYAMA, Yoshiaki
openaire +2 more sources
Semmaphorin 3 A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8<sup>+</sup> T cells. [PDF]
Barnkob MB +27 more
europepmc +1 more source
Reduced expression of semaphorin 3A in osteoclasts causes lymphatic expansion in a Gorham-Stout disease (GSD) mouse model. [PDF]
Zhang D +10 more
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The role of Semaphorin 3A in oral diseases
Oral Diseases, 2023AbstractSemaphorin 3A (SEMA3A), also referred to as H‐Sema III, is a molecule with significant biological importance in regulating physiological and pathological processes. However, its role in oral diseases, particularly its association with inflammatory immunity and alveolar bone remodeling defects, remains poorly understood.
Xinyue Zhang +3 more
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Osteoprotection by semaphorin 3A
Nature, 2012The bony skeleton is maintained by local factors that regulate bone-forming osteoblasts and bone-resorbing osteoclasts, in addition to hormonal activity. Osteoprotegerin protects bone by inhibiting osteoclastic bone resorption, but no factor has yet been identified as a local determinant of bone mass that regulates both osteoclasts and osteoblasts ...
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Semaphorin 3A: an immunoregulator in systemic sclerosis
Rheumatology International, 2015Semaphorin 3A (sema3A) plays a regulatory role in immune responses, mainly affecting the activation of regulatory T cells. It has been found to correlate with disease activity in rheumatoid arthritis and systemic lupus erythematosus (SLE). To investigate the expression of sema3A in patients with systemic sclerosis (SSc) compared to healthy controls and
Doron, Rimar +10 more
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The Role Of Semaphorin 3A In The Skeletal System
Critical Reviews in Eukaryotic Gene Expression, 2015Semaphorin 3A (Sema3A), characterized by a conserved N-terminal "Sema" domain, was originally described as an axon guidance molecule. Recent research indicates that it performs a critical function in the skeletal system. This review highlights recent advances in understanding of the role of Sema3A in the skeletal system as a regulator of bone ...
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