Axon-dendrite polarity is likely instructed by extrinsic cues in the developing nervous system, though the mechanisms governing this process remain to be fully elucidated. In this issue of Neuron, Shelly et al.
Audrey S. Howell +3 more
core +1 more source
Semaphorin 3A-Neuropilin-1 Signaling Modulates MMP13 Expression in Human Osteoarthritic Chondrocytes. [PDF]
Stöckl S +4 more
europepmc +1 more source
The formation of a complicate nervous system requires precise navigation and elaboration for growth cone and dendrites to connect to their target.
core
Osseointegration of Titanium Implants in a Botox-Induced Muscle Paralysis Rat Model Is Sensitive to Surface Topography and Semaphorin 3A Treatment. [PDF]
Deng J +6 more
europepmc +1 more source
Inhibition of pathological retinal neovascularization by semaphorin 3A.
Pathological retinal angiogenesis is a major cause of vision loss. Semaphorin 3A (Sema3A), a chemorepellent guidance protein, plays crucial roles in neural and vascular patterning. To identify its role in retinal neovascularization, we investigated its antiangiogenic effects.Human umbilical vein endothelial cells (HUVECs) were used for the in vitro ...
Wenzhen, Yu +6 more
openaire +1 more source
Semaphorin 3A delivered by a rapidly polymerizing click hydrogel overcomes impaired implant osseointegration in a rat type 2 diabetes model. [PDF]
Deng J +6 more
europepmc +1 more source
Semaphorin-3A, a regulator of immune system
Background: Atherosclerosis a global health issue and first leading of myocardial infarction and strokes is an immunity-related disease. Recent data indicate that neural guidance molecules including Semaphorin-3A have immune regulation function.
Heidari, Maryam
core
Efficacy of an Anti-Semaphorin 3A Neutralizing Antibody in a Male Experimental Retinal Vein Occlusion Mouse Model. [PDF]
Nakamura S +6 more
europepmc +1 more source
miR-181b targets semaphorin 3A to mediate TGF-β-induced endothelial-mesenchymal transition related to atrial fibrillation. [PDF]
Lai YJ +6 more
europepmc +1 more source

