Results 101 to 110 of about 117,092 (200)

Neuron-Derived Semaphorin 3A Is an Early Inducer of Vascular Permeability in Diabetic Retinopathy via Neuropilin-1

open access: yes, 2013
SummaryThe deterioration of the inner blood-retinal barrier and consequent macular edema is a cardinal manifestation of diabetic retinopathy (DR) and the clinical feature most closely associated with loss of sight. We provide evidence from both human and
Leboeuf, Dominique   +13 more
core   +1 more source

Inflammation and itching in patients suffering from atopic dermatitis and psoriasis. Assessment of the expression of neurotrophins аnd neuropeptides

open access: yesVestnik Dermatologii i Venerologii, 2017
Goal. To assess the expression of neurotrophin, a nerve growth factor, amphiregulin, an epidermal growth factor, semaphorin 3A, a nerve repulsion factor, and PGP9.5 protein, a nerve fiber marker, in the skin of patients suffering from atopic dermatitis ...
V. A. Smolyannikova   +3 more
doaj   +1 more source

Plexin-Neuropilin-1 Complexes Form Functional Semaphorin-3A Receptors

open access: yes, 1999
Class 1 and 3 semaphorins repulse axons but bind to different cell surface proteins. We find that the two known semaphorin-binding proteins, plexin 1 (Plex 1) and neuropilin-1 (NP-1), form a stable complex.
Takahashi, Takuya   +7 more
core   +1 more source

SEMAPHORIN 3A - A NEW INTRATHYMIC SUPPRESSOR FACTOR

open access: yesMedical academic journal, 2019
Semaphorins were originally identified as axon guidance factors involved in the development of the neuronal system. However, accumulating evidence indicates that several semaphorins, so-called ‘immune semaphorins’, are also involved in various phases of immune responses.
K V Rutto, E P Kisseleva
openaire   +2 more sources

Expression analysis and possible functional roles of semaphorin/plexin/CRMP families in mouse pancreatic islets

open access: yesScientific Reports
Semaphorins were initially identified as axon guidance molecules that were widely expressed and involved in divergent functions in various organs, including neuronal development and immunological processes.
Mayu Kyohara   +13 more
doaj   +1 more source

Human Muscle Progenitor Cells Displayed Immunosuppressive Effect through Galectin-1 and Semaphorin-3A

open access: yesStem Cells International, 2012
In human skeletal muscle, myoblasts represent the main population of myogenic progenitors. We previously showed that, beside their myogenic differentiation capacities, myoblasts also differentiate towards osteogenic and chondrogenic lineages, some ...
Séverine Lecourt   +10 more
doaj   +1 more source

Semaphorin-7A diminishes HLF proliferation and migration.

open access: yes, 2017
HLF derived from non-fibrotic lungs were treated with either control or semaphorin-7A siRNA and cultured in 1% or 10% FBS for 48 h. A/ BrdU was incubated with cells for 6 h.
Elizabeth A. Kelly (429798)   +6 more
core   +1 more source

Investigation of the effects of semaphorin 3A on new bone formation in a rat calvarial defect model

open access: yes, 2019
Purpose: This study investigates the effects of semaphorin 3A on new bone formation in an experimental rat ...
Onur, Özen   +8 more
core   +1 more source

Podocyte Shape Regulation by Semaphorin 3A and MICAL-1 [PDF]

open access: yes, 2016
Podocytes are complex epithelial cells with foot processes that are essential for the integrity and function of the kidney glomerular filters. Podocyte foot processes linked by slit diaphragms constitute signaling platforms that tightly regulate the cell shape and the function of the filtration barrier.
openaire   +2 more sources

Role of calpain-mediated p53 truncation in semaphorin 3A-induced axonal growth regulation

open access: yes, 2010
Neurite outgrowth represents a critical stage in the correct development of neuronal circuitries, and is dependent on the complex regulation of actin filament and microtubule dynamics by intrinsic as well as extrinsic signals.
Xiaoning Bi   +3 more
core   +1 more source

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