Results 91 to 100 of about 117,092 (200)
Regulation of antitumour CD8 T-cell immunity and checkpoint blockade immunotherapy by Neuropilin-1
Nature Communications, 2019 Neuropilin-1 (Nrp-1) is a marker for CD4 + regulatory T cells. Here the authors show that Nrp-1 is co-expressed with PD-1 on a subset of CD8 tumour-infiltrating T lymphocytes and inhibits T-cell migration and cytotoxicity when bound by its ligand ...
Marine Leclerc +7 more
doaj +1 more source
Clinical &Translational Immunology, Volume 15, Issue 5, 2026.Abstract Objectives CD4+ T cells play key roles in regulating immune responses during pregnancy; therefore, we aimed to understand the CD4+ T‐cell surface proteome and transcriptome during pregnancy. Methods CD4+ T cells were analysed in blood and decidua from term pregnancies (> 37 weeks) and non‐pregnant blood.
Jennifer R Habel +17 more
wiley +1 more source
, 2005 Bone tissue is densely innervated, and there is increasing evidence for a neural control of bone metabolism. Semaphorin-3A is a very important regulator of neuronal targeting in the peripheral nervous system as well as in angiogenesis, and knockout of ...
Malaval, Luc +17 more
core +1 more source
Recent Advances in Natural Polymers‐based Hydrogels for Periodontal Regeneration
Macromolecular Bioscience, Volume 26, Issue 5, May 2026.Natural polymer‐based hydrogels are emerging as promising biomimetic platforms for periodontal regeneration. This review highlights advances in alginate, collagen, and chitosan hydrogels engineered to modulate inflammation, deliver bioactive agents, and support tissue repair.
João de Freitas Gomes Neto +7 more
wiley +1 more source
Semaphorin 3A serum levels are influenced by haemodialysis: what clinical significance?
, 2015 AIM: Semaphorin 3A urinary levels represent an early, predictive biomarker of acute kidney injury and positively correlate with albumin-to-creatinine ratio and serum creatinine in hypertensive patients with chronic kidney disease. Our purpose has been to
Visconti, Luca +8 more
core +1 more source
Modeling Synaptic Maturation From Growth Cone to Synapse in Human Organoids
Journal of Neurochemistry, Volume 170, Issue 5, May 2026.Synapses are implicated in several neurological disorders and psychiatric diseases. The emergence and wide use of neural organoids provide a new opportunity to study human synapses in healthy and disease settings. Therefore, we developed a simple method for the enrichment of synaptosomes and growth cone particles from forebrain organoids. The method is
Marie S. Øhlenschlæger +16 more
wiley +1 more source
Control of human thymocyte migration by Neuropilin-1/Semaphorin-3A mediated interactions. [PDF]
, 2007 It is largely established that molecules first discovered in the nervous system are also found in the immune system. Neuropilin-1 (NP-1) was initially identified to mediate semaphorin-induced chemorepulsion during brain development and is also involved ...
Dardenne, M. +23 more
core +1 more source
Semaphorin 3A controls allergic and inflammatory responses in experimental allergic conjunctivitis
International Journal of Ophthalmology, 2015 AIM: To assess the efficacy of topical Semaphorin-3A (SEMA3A) in the treatment of allergic conjunctivitis. METHODS: Experimental allergic conjunctivitis (EAC) mice model induced by short ragweed pollen (SRW) in 4-week-old of BALB/c mice, mice were ...
Junmi Tanaka +10 more
doaj +1 more source
Semaphorin-3A is expressed by tumor cells and alters T-cell signal transduction and function
, 2006 An important aspect of tumor progression is the ability of cancer cells to escape detection and clearance by the immune system. Recent studies suggest that several tumors express soluble factors interfering with the immune response.
Tamagnone, Luca
core +1 more source
Semaphorin 3A and VEGF promote inflammation in retinopathy
The FASEB Journal, 2015 Immunological activity in the CNS is largely dependent on an innate immune response and is present in health and heightened in diseases such as diabetic retinopathy, multiple sclerosis, amyotrophic...
Przemyslaw Sapieha +2 more
openaire +1 more source